Progesterone and abnormal uterine bleeding/menstrual disorders

Michaela Jewson, Prashant Purohit, Mary Ann Lumsden
Best practice & research. Clinical obstetrics & gynaecology · 2020 · vol. 69 , pp. 62–73 · doi:10.1016/j.bpobgyn.2020.05.004 · PMID:32698992 · W3032934861
Review OA: closed CC0 ⤵ 9 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This paper reviews the role of progesterone in abnormal uterine bleeding and menstrual disorders, focusing on its therapeutic applications and mechanisms of action.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

This chapter explores the role of progesterone and progestogens in the management of abnormal uterine bleeding (AUB). Progestogens are used to regulate intermenstrual bleeding and decrease heavy menstrual bleeding (HMB) in women of reproductive age or who are perimenopausal. In menopausal women, progesterones and progestogens prevent endometrial hyperplasia and aim to reduce the development of endometrial cancer. We hope to make clear current best practice including preparation, specific benefits and risks. Progesterone also acts in concert with other hormones to affect breast, cardiovascular system, lipid profile and bone. We hope to explain how its unintended side effects may be used beneficially or may cause intended side effects.

My notes (saved in your browser only)

MeSH descriptors

Menorrhagia Metrorrhagia Female Humans Progesterone Progesterone Progestins Progestins Uterine Hemorrhage Uterine Hemorrhage

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (48)

Cited by (9)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:28:03.990958+00:00
unpaywall
last seen: 2026-10-13T06:25:51.201866+00:00
License: CC0 · commercial use OK