Endometriosis Involving the Sciatic Nerve: A Case Report of Isolated Endometriosis of the Sciatic Nerve and Review of the Literature
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This case report describes isolated sciatic nerve endometriosis causing hip and buttock pain, which was diagnosed via MRI and successfully treated with laparoscopic excision.
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Abstract
Endometriosis is a common gynecological condition which affects 5–10% of women of reproductive age and up to 50% of women with pelvic pain and infertility. The most commonly affected areas are the pelvic peritoneum, ovaries and rectovaginal septum. Isolated endometriosis of the sciatic nerve is very rare. Our patient suffered from worsening right hip and buttock pain with severe exacerbation during menstruation. Several different imaging modalities (ultrasound of her pelvis and right hip, as well as X-rays and computed tomography scans of her right hip and lumbosacral spine) failed to identify any pathology. Magnetic resonance imaging scans of her pelvis revealed a 3.5 cm endometriotic lesion over the pelvic segment of her right sciatic nerve. Following a multidisciplinary discussion, the patient underwent laparoscopic excision of endometriosis. The patient recovered well from her surgery. She successfully conceived with in vitro fertilization 3 years after her surgery, following a failed course of Clomid (Clomiphene citrate) for ovulatory dysfunction.
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References (16)
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Cited by (16)
- Left-Sided Sciatic Nerve Endometriosis Presenting As Chronic Thigh Pain and Muscle Atrophy: A Case Report 2026
- Literature update and MRI case collection of unusual localizations 2025
- Case reports and literature review of neuro-endometriosis: beyond degenerative spine disease 2025
- Extragenital and Extrapelvic Endometriosis: Literature Update and Mri Immaging Case Collection of Unusual Localizations 2025
- Sciatic nerve endometriosis – The correct approach matters: A case report 2023
- Sciatic Endometriosis 2023
- Rare extragenital endometriosis: pathogenesis and therapy 2022
- Comparison of Isolated Sciatic Nerve and Sacral Nerve Root Endometriosis: A Review of the Literature 2022
- Pelvic Nerve Endometriosis (Neuropelveology) 2022
- Endometriosis of the sciatic nerve masquerading as lumbar spondylosis in a 40-year-old Chinese woman 2021
- Endometriosis con infiltración aislada del nervio ciático, una forma de presentación atípica. Reporte de un caso clínico 2021
- Diagnosis and Management of Sciatic Endometriosis at the Greater sciatic Foramen: a Case Report 2021
- Laparoscopic “Shaving” for Infiltrative External Adenomyosis of Bowel Muscularis and Concomitant Deep Infiltrating Endometriosis 2021
- Carcinoma arising within sciatic nerve endometriosis: a case report 2021
- Sciatic endometriosis: A narrative review of an unusual neurogynecologic condition 2020
- Extrapelvic Sciatic Nerve Endometriosis, the Role of Magnetic Resonance Imaging: Case Report and Systematic Review 2019
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- europepmc
- last seen: 2026-06-04T01:30:01.192114+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-05-13T22:19:31.300640+00:00
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