Ovarian clear cell carcinoma arising in a large endometrioma - A case report with pathological correlation and literature review

Eduardo Negrão, Beatriz Flor de Lima, Beatriz Flor-de-Lima, Ana Luísa Duarte, Ana Costa Braga, Raquel Portugal, António J Madureira
Radiology case reports · 2022 · vol. 17(8) , pp. 2806–2811 · doi:10.1016/j.radcr.2022.05.015 · PMID:35694637 · PMC9184296 · W4282032129
case-report OA: gold CC0
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This case report details a 52-year-old woman with ovarian clear cell carcinoma arising in a large endometrioma, highlighting MRI's role in detecting suspicious features for early diagnosis.

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Abstract

Endometriosis-associated ovarian cancer represents the most common form of malignancy associated with this benign disease. It has a better prognosis than most types of ovarian cancer, with endometrioid adenocarcinoma and clear cell carcinoma as the main histological types. Clinical presentation is usually nonspecific and tumor biomarkers can be misleading, since they can also be elevated in the presence of benign ovarian endometriosis. We report a case of a 52-year-old woman with known ovarian and deep pelvic endometriosis, who developed ovarian clear cell carcinoma within a large endometrioma. The imaging findings highlight the key role of magnetic resonance imaging in detecting suspicious features such as loss of the "T2 shading" sign, loss of high T1 signal of an endometrioma, or the presence of mural nodules. Early detection of these malignancies is fundamental for adequate surgical treatment and overall outcome.

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Condition tags

endometriosisendometrioma

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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License: CC0 · commercial use OK