Additional file 2 of Gut microbiome in endometriosis: a cohort study on 1000 individuals

Inmaculada Pérez‐Prieto, Vargas, Eva, Salas-Espejo, Eduardo, Lüll, Kreete, Canha-Gouveia, Analuce, Pérez, Laura Antequera, Fontes, Juan, Salumets, Andres, Andreson, Reidar, Aasmets, Oliver, Whiteson, Katrine, Org, Elin, Altmäe, Signe
2024 · doi:10.6084/m9.figshare.26750459.v1 · W6939905317
dataset OA: green CC0
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study analyzed gut microbiome compositions, including species, KEGG orthologs, and EggNOG orthologs, between endometriosis and control groups, with sensitivity analyses and estrogen pathway enzyme comparisons.

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Abstract

Additional file 2: Tables S1-S7. Table S1- Correlation analysis between gut enterotypes and clinical factors. Table S2- Differential abundance analysis in endometriosis and control groups. Species with a prevalence > 10% and relative abundance ≥ 0.1% were compared in endometriosis and control groups using an Analysis of Compositions of Microbiomes with Bias Correction (ANCOM-BC). Table S3- Differential abundance analysis in endometriosis and control groups. KEGG orthologs (KO) with a prevalence > 10% and relative abundance ≥ 0.1% were compared in endometriosis and control groups using an Analysis of Compositions of Microbiomes with Bias Correction (ANCOM-BC). Table S4- Differential abundance analysis in endometriosis and control groups. EggNOG orthologs with a prevalence > 10% and relative abundance ≥ 0.1% were compared in endometriosis and control groups using an Analysis of Compositions of Microbiomes with Bias Correction (ANCOM-BC). Table S5- Sensitivity differential abundance analysis in endometriosis and control groups. Species with a prevalence > 10% and relative abundance ≥ 0.1% were compared in endometriosis and control groups after excluding women with age > 50, using an Analysis of Compositions of Microbiomes with Bias Correction (ANCOM-BC). Table S6- Sensitivity differential abundance analysis in endometriosis and control groups. KEGG orthologs (KO) with a prevalence > 10% and relative abundance ≥ 0.1% were compared in endometriosis and control groups after excluding women with age > 50, using an Analysis of Compositions of Microbiomes with Bias Correction (ANCOM-BC). Table S7- Estrogen path enzymes with ALDEx2 analysis between endometriosis and control groups.

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Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (56)

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