Adenomyosis: Diagnosis and Management.
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Adenomyosis, characterized by endometrial glands within the myometrium, presents with symptoms like heavy bleeding or pain and is diagnosed via imaging, with treatment options ranging from hormonal suppression to hysterectomy.
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Abstract
Adenomyosis is a clinical condition where endometrial glands are found in the myometrium of the uterus. One in three patients with adenomyosis is asymptomatic, but the rest may present with heavy menstrual bleeding, pelvic pain, or infertility. Heavy menstrual bleeding is the most common symptom. Adenomyosis is distinct from endometriosis (the presence of endometrial glands outside of the uterus), but the two conditions often occur simultaneously. Risk factors for developing adenomyosis include increasing age, parity, and history of uterine procedures. Most patients are diagnosed from 40 to 50 years of age, but younger patients with infertility are increasingly being diagnosed with adenomyosis as imaging modalities improve. Diagnosis of adenomyosis begins with clinical suspicion and is confirmed with transvaginal ultrasonography and pelvic magnetic resonance imaging. Treatment of adenomyosis typically starts with hormonal menstrual suppression. Levonorgestrel-releasing intrauterine systems have shown some effectiveness. Patients with adenomyosis may ultimately have a hysterectomy if symptoms are not controlled with medical therapy.
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Cited by (16)
- Image-guided cryoablation for uterine diseases: a systematic review 2025
- Improved surgical outcomes in adenomyosis: a novel insight into the superiority of secretory phase adenomyomectomy 2025
- Identification of novel causally related genes in adenomyosis: An integrated summary data-based Mendelian randomization study and bioinformatics analysis 2025
- Differences in the Sonographic Features of Adenomyosis and Concurrent Endometriosis Compared to Isolated Adenomyosis 2025
- Uterine Artery Embolization as an Alternative Therapeutic Option in Adenomyosis: An Observational Retrospective Single-Center Study 2025
- Perspectives in transvaginal sonography for the diagnosis of adenomyosis 2025
- Validation of the revised MUSA criteria for sonographic detection of adenomyosis 2025
- Efficacy of etonogestrel subcutaneous implants versus the levonorgestrel-releasing intrauterine system in the conservative treatment of adenomyosis 2024
- The Cellular Respiration of Endometrial Biopsies from Patients with Various Forms of Endometriosis 2024
- Effects of Shixiao Huoxue Decoction on pain, tumor necrosis factor-α, and interleukin-8 in patients with adenomyosis 2024
- Molecular Imaging in Gynecology: Beyond Cancer 2024
- Uterine cystic adenomyosis: a case report 2024
- Correlation between the Systemic Immunoinflammatory Index and Platelet–Lymphocyte Ratio in Patients with Adenomyosis 2024
- Effects of different treatment methods on clinical efficacy and fertility outcomes of patients with adenomyosis 2024
- Exosomes: potential diagnostic markers and drug carriers for adenomyosis 2023
- Establishment and validation of a nomogram model for predicting adverse pregnancy outcomes of pregnant women with adenomyosis 2023
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- last seen: 2026-06-04T01:30:01.192114+00:00
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