Comparable Effects of the Androgen Derivatives Danazol, Oxymetholone and Nandrolone on Telomerase Activity in Human Primary Hematopoietic Cells from Patients with Dyskeratosis Congenita

Margherita Vieri, Martin Kirschner, Mareike Tometten, Anne Abels, Benjamin Rolles, Susanne Isfort, Jens Panse, Tim H. Brümmendorf, Fabian Beier
In: International Journal of Molecular Sciences · 2020 · vol. 21(19) , pp. 7196 · doi:10.3390/ijms21197196 · PMID:33003434 · W3090851370
article OA: gold CC0 ⤵ 2 in-corpus citations
🔓 Open OA copy View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

Danazol, oxymetholone, and nandrolone similarly enhanced telomerase activity in human hematopoietic cells from dyskeratosis congenita patients in vitro.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

in AD mechanism of action. In conclusion, no significant differences in the ability to functionally enhance telomerase activity could be observed for the three AD studied in vitro. Physicians therefore might choose treatment based on patients' individual co-morbidities, e.g., pre-existing liver disease and expected side-effects.

My notes (saved in your browser only)

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (35)

Cited by (2)

Source provenance

openalex
last seen: 2026-05-13T19:33:11.649412+00:00
License: CC0 · commercial use OK