Jens Panse

ORCID: 0000-0001-6316-3112 · 1 paper in corpus

lab-animal 2020

Comparable Effects of the Androgen Derivatives Danazol, Oxymetholone and Nandrolone on Telomerase Activity in Human Primary Hematopoietic Cells from Patients with Dyskeratosis Congenita

International journal of molecular sciences ·doi:10.3390/ijms21197196

Dyskeratosis congenita (DKC) is a rare inherited disease of impaired telomere maintenance that progressively leads to multi-organ failure, including the bone marrow. By enhancing telomerase activity, androgen derivatives (ADs) are a potenti…