Combined laparoscopic surgery and danazol therapy for pelvic endometriosis
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This study investigated the combined effects of laparoscopic surgery and danazol treatment on pelvic endometriosis.
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Abstract
The role of combined laparoscopic surgery and postoperative danazol treatment for endometriosis in infertile patients has been reviewed in 66 cases. Thirty-five patients with mild endometriosis and twenty-five patients with moderate endometriosis received a standardized laparoscopic surgical procedure followed by danazol therapy with a minimum of 6 months' follow-up. Six patients with severe endometriosis received 4 months of danazol treatment followed by conservative surgery. Fifty-four per cent of these patients conceived, with 92% delivering a live child. By excluding patients with other significant infertility factors, a "corrected" fertility rate of 68% was obtained. The majority of patients conceiving after danazol treatment did so within the first 6 months after therapy. Reported complications to drug treatment were minimal. Second-look laparoscopy when performed in patients who had not conceived within 6 months revealed a significant decrease in residual endometriosis.
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Cited by (31)
- Reoperation After Minimally Invasive Endometriosis Surgery: A Phenotype-Specific Meta-analysis of 22,644 Patients 2026
- Effects of 3 month therapy with danazol after laparoscopic surgery for stage III/IV endometriosis: a randomized study 1999
- Endometriosis 1996
- Recurrent Endometriosis 1995
- Gynecology 1995
- The History of Surgical Treatment of Endometriosis 1995
- Treatment of Infertility Associated With Endometriosis 1995
- Recurrent Endometriosis 1995
- Gynecologic Disorders 1992
- Laser laparoscopic management of large endometriomas 1992
- Laser laparoscopic management of large endometriomas 1991
- Operative Eingriffe bei der Endometriose 1991
- Macro- and microsurgical treatment of endometriosis 1991
- The Surgical Management of Endometriosis 1989
- Laparoscopic laser treatment of endometriosis with the Nd: YAG sapphire probe 1989
- Endometriosis 1989
- I.V.F. Treatment Following Danazol Priming in a Patient with Severe Endometriosis 1989
- LAPAROSCOPIC TREATMENT OF ENDOMETRIOSIS 1989
- Endometriosis of the urinary tract 1988
- Comparison of different modalities of treatment for minimal and mild endometriosis 1988
- Danazol and medroxyprogesterone acetate inefficacious in the treatment of infertility in endometriosis 1988
- The importance of laparoscopic coagulation of mild endometriosis in infertile women. 1987
- Placebo-controlled comparison of danazol and high-dose medroxyprogesterone acetate in the treatment of endometriosis 1987
- Surgical treatment of endometriosis via laser laparoscopy 1986
- Endometriosis y factor tubo peritoneal 1986
- Mild endometriosis and ovulatory dysfunction: effect of danazol treatment on success of ovulation induction 1986
- Endometriosis 1986
- Danazol in the treatment of endometriosis: analysis of 100 cases with a 4-year follow-up 1985
- Endometriosis 1984
- Regression of endometriosis following shorter treatment with, or lower dose of danazol: Comparison of pre‐ and post‐treatment laparoscopic findings in the Scandinavian multi‐center study 1984
- Medical treatment of endometriosis in infertile patients 1983
Source provenance
- europepmc
- last seen: 2026-07-27T06:15:28.040536+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:10:06.101301+00:00
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