Adenomyosis in Reproductive Years: Fertility and ART in Adenomyosis

Adenomyosis was thought to be present only in parous women. However, with the routine use of transvaginal ultrasound in infertility practice, the burden of adenomyosis in the infertile population has become more evident. The prevalence of adenomyosis was found to be 24.4% and 22% in women aged ≥40 years and ≤40 years in patients prior to reproductive treatment, respectively. This was found to be higher in women with recurrent pregnancy loss (38.2%) and previous ART failure (34.7%) when compared with the rest. Various mechanisms causing infertility are proposed by different authors, and any or a combination of many of these can lead to this dreadful condition. The treatment options for such cases depend on the woman’s age, reproductive status, and clinical symptoms. Many different medical and surgical methods are being offered, but there is still no drug specific for adenomyosis. Many medications are used off-label to manage pain and bleeding and sometimes even improve fertility outcome. The most commonly used and studied drug is GnRH agonist, but as it has negative effects in IVF cycles, it can be used after ovarian stimulation and before a frozen embryo transfer. Surgery for adenomyosis is less popular but yet a valid option. There is no conclusive evidence of a “best” method, and proper randomized studies targeting impact on fertility are lacking. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others Change history 10 September 2022 Correction to:

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