Endosalpingiosis and chronic pelvic pain.
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Endosalpingiosis is more common than previously thought and can be found alone or with endometriosis, potentially causing chronic pelvic pain.
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Abstract
OBJECTIVE: To show that endosalpingiosis (ES) is a frequently underdiagnosed or misdiagnosed entity in women thought to have endometriosis (EM) on initial pathologic review and that ES alone may be an independent cause of pelvic pain. STUDY DESIGN: A retro-spective review of pathology records from gynecologic cases from June 1992 to November 1994 revealed 37 cases of EM and 5 cases of ES. These cases were reviewed by a single pathologist (J.M.), who assigned a final diagnosis. Preoperative diagnosis or symptoms that led to surgery were compared to the initial and final pathologic diagnoses. RESULTS: Of the 37 cases with the initial diagnosis of EM, 64.9% had EM only (group I), 18.9% had both EM and ES (group II), and 16.2% had ES alone (group III). Of the five patients with an initial diagnosis of ES, 80% had ES (group IV), while 20% had both ES and EM (group V). In patients who had ES as their final diagnosis (group III and IV), 70% had chronic pelvic pain or presumed endometriosis as a preoperative diagnosis. This was similar to the 53.1% of patients with a final diagnosis of EM who had the same preoperative diagnosis. CONCLUSION: We conclude that ES is more common than once thought. Furthermore, when an initial diagnosis of EM is made, further review may reveal that many of these cases are a combination of both EM and ES, while still others may be ES alone. ES, which has been long been thought to be clinically insignificant, could be a source of pelvic pain.
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Cited by (16)
- The association of endosalpingiosis with chronic pelvic pain 2023
- Vaginal Endosalpingiosis: A Case Report and Literature Review 2022
- Endosalpingiose – ein irrelevanter laparoskopischer Zufallsbefund? 2021
- Incidental primary peritoneal serous borderline tumor miming endometriosis during laparoscopy for chronic pelvic pain 2020
- Endosalpingiosis: More than just an incidental finding at the time of gynecologic surgery? 2016
- Tubal origin of ovarian endometriosis and clear cell and endometrioid carcinoma. 2015
- Endosalpingiosis in Postmenopausal Elderly Women 2014
- Review Article Cell origin of endometriosis: contribution by the fallopian tube epithelium 2013
- What is endosalpingiosis? 2012
- Histopathologic findings on uterosacral ligaments in women with chronic pelvic pain and visually normal pelvis at laparoscopy 2006
- The Development of a Mouse Model of Ovarian Endosalpingiosis 2005
- Small Echogenic Foci in the Ovaries 2004
- The Role of Laparoscopy in the Chronic Pelvic Pain Patient 2003
- Clinical Outcome in Female Patients with Pelvic Pain and Normal Pelvic US Findings 2000
- The importance of histological diagnosis in patients with chronic pelvic pain and laparoscopic evidence of endometriosis 2000
- Endosalpingiosis: Clinical Presentation and Follow-Up 1998
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- europepmc
- last seen: 2026-08-08T06:08:32.324769+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:10:46.468712+00:00
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