An Introduction

In: Focused Ultrasound Surgery in Gynecology · 2021 · pp. 1–12 · doi:10.1007/978-981-16-0939-8_1 · W4245394285
book-chapter OA: closed CC0
Full text JSON View on OpenAlex View at publisher
AI-generated summary by claude@2026-06+body, 2026-06-09

Focused ultrasound uses high-frequency sound waves to noninvasively treat solid tumors and benign gynecologic diseases by thermally ablating targeted tissue.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

AI-generated deep summary by claude@2026-06, 2026-06-10 · read from full text

This paper is an introductory chapter explaining ultrasound and high-intensity focused ultrasound (HIFU), including how focused ultrasound is delivered from an external transducer to a focal point inside the body and how thermal, cavitation, and mechanical effects can produce coagulation necrosis. It describes HIFU as a noninvasive procedure used across a range of benign gynecologic conditions and solid tumors. The chapter does not present new experimental data and provides no detailed methodological caveats, functioning instead as a conceptual overview with example references. Relevance to endometriosis: the chapter explicitly cites adenomyosis as one of the benign gynecologic diseases treated with HIFU, though its main focus is a general introduction to focused ultrasound surgery rather than endometriosis-specific mechanisms or outcomes.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Full text 4,658 characters · extracted from oa-doi-fallback · 2 sections · click to expand

Abstract

When an object vibrates between 20 and 20,000 Hz, it produces an audible sound. In simple terms, sound is a vibration that can be picked up by our ears. Ultrasound is a sound wave with a frequency higher than 20,000 Hz (Fig. 1.1), which is higher than the upper audible limit of hearing. Thus, it cannot be heard by the human ear. Focused ultrasound is a noninvasive treatment procedure that uses ultrasound waves emitted from a transducer outside the body using its penetration and focusing ability to form a focus inside the body. When ultrasound waves fire, a combination of thermal, cavitation, and mechanical effects of the ultrasonic wave produce instantaneous high temperature at the focal point to cause coagulation necrosis of the target tissue. Focused ultrasound is used for the treatment of benign gynecologic diseases including uterine fibroids [1], adenomyosis [2], cesarean scar pregnancy [3] and placenta accreta [4] as well as liver cancer [5], breast cancer [6], pancreatic cancer [7], bone cancer [8], retroperitoneal sarcoma [9], and other solid tumors [10]. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

References

Marinova M, et al. Novel non-invasive treatment with high-intensity focused ultrasound (HIFU). Ultraschall Med. 2016;37(1):46–55. Shui L, et al. High-intensity focused ultrasound (HIFU) for adenomyosis: two-year follow-up results. Ultrason Sonochem. 2015;27:677–81. Huang L, Du Y, Zhao C. High-intensity focused ultrasound combined with dilatation and curettage for cesarean scar pregnancy. Ultrasound Obstet Gynecol. 2014;43(1):98–101. Lee J-S, et al. High-intensity focused ultrasound combined with hysteroscopic resection to treat retained placenta accreta. Obstet Gynecol Sci. 2016;59(5):421–5. Aubry J-F, et al. The road to clinical use of high-intensity focused ultrasound for liver cancer: technical and clinical consensus. J Ther Ultrasound. 2013;1(1):13. Li S, Wu P-H. Magnetic resonance image-guided versus ultrasound-guided high-intensity focused ultrasound in the treatment of breast cancer. Chin J Cancer. 2013;32(8):441. Dababou S, et al. A meta-analysis of palliative treatment of pancreatic cancer with high intensity focused ultrasound. J Ther Ultrasound. 2017;5(1):9. Li C, et al. Non-invasive treatment of malignant bone tumors using high-intensity focused ultrasound. Cancer. 2010;116(16):3934–42. Thompson SM, et al. Image-guided thermal ablative therapies in the treatment of sarcoma. Curr Treat Options Oncol. 2017;18(4):25. Maloney E, Hwang JH. Emerging HIFU applications in cancer therapy. Int J Hyperth. 2015;31(3):302–9. Stewart EA, et al. Sustained relief of leiomyoma symptoms by using focused ultrasound surgery. Obstet Gynecol. 2007;110(2 Part 1):279–87. Schlesinger D, et al. MR-guided focused ultrasound surgery, present and future. Med Phys. 2013;40(8):080901. Zini C, et al. Ultrasound-and MR-guided focused ultrasound surgery for prostate cancer. World J Radiol. 2012;4(6):247. Merckel LG, et al. MR-guided high-intensity focused ultrasound ablation of breast cancer with a dedicated breast platform. Cardiovasc Intervent Radiol. 2013;36(2):292–301. Yiallouras C, Damianou C. Review of MRI positioning devices for guiding focused ultrasound systems. Int J Med Robotics Comput Assist Surg. 2015;11(2):247–55. Hesley GK, et al. A clinical review of focused ultrasound ablation with magnetic resonance guidance: an option for treating uterine fibroids. Ultrasound Q. 2008;24(2):131–9. Wang W, et al. Safety and efficacy of US-guided high-intensity focused ultrasound for treatment of submucosal fibroids. Eur Radiol. 2012;22(11):2553–8. Chen J, et al. Safety of ultrasound-guided ultrasound ablation for uterine fibroids and adenomyosis: a review of 9988 cases. Ultrason Sonochem. 2015;27:671–6. Zhang L, et al. Ultrasound-guided high intensity focused ultrasound for the treatment of gynaecological diseases: a review of safety and efficacy. Int J Hyperth. 2015;31(3):280–4. Author information Authors and Affiliations Corresponding author Rights and permissions Copyright information © 2021 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. About this chapter Cite this chapter Wong, F., Zhang, L., Wang, Z. (2021). An Introduction. In: Focused Ultrasound Surgery in Gynecology. Springer, Singapore. https://doi.org/10.1007/978-981-16-0939-8_1 Download citation DOI: https://doi.org/10.1007/978-981-16-0939-8_1 Published: Publisher Name: Springer, Singapore Print ISBN: 978-981-16-0938-1 Online ISBN: 978-981-16-0939-8 eBook Packages: MedicineMedicine (R0)

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (4)

References (19)

Source provenance

openalex
last seen: 2026-06-04T00:00:01.174412+00:00
unpaywall
last seen: 2026-05-20T11:00:21.680559+00:00
License: CC0 · commercial use OK