Novel Non-invasive Treatment With High-intensity Focused Ultrasound (HIFU)

Milka Marinova, M Marinova, M Rauch, Maximilian Rauch, Hans H. Schild, H H Schild, H M Strunk, Holger Strunk
Ultraschall in der Medizin (Stuttgart, Germany : 1980) · 2015 · vol. 37(01) , pp. 46–55 · doi:10.1055/s-0035-1553318 · PMID:26251996 · W2301295570
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Abstract

Ultrasound is not only used for diagnostic purposes but it also can be applied therapeutically so far that nowadays high-intensity focused ultrasound (HIFU) even represents a novel non-invasive treatment modality for various solid tumors. HIFU works by causing selectively deep tissue destruction of target lesions within the body without harming adjacent and overlying structures. In this article, we present an overview on both the mode of action and requirements for a HIFU treatment as well as on the safety and the current status of indications and possible applications with regard to benign and malignant gynecological diseases. Based on numerous studies and original articles, HIFU proved to be an effective and low-risk treatment option particularly for uterine fibroids and adenomyosis, but it also seems to be effective for breast fibroadenomas or even for breast cancer in special cases and other rare entities.

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Condition tags

adenomyosis

MeSH descriptors

Genital Diseases, Female Genital Neoplasms, Female High-Intensity Focused Ultrasound Ablation Adenomyosis Adenomyosis Breast Neoplasms Breast Neoplasms Female Fibroadenoma Fibroadenoma Genital Diseases, Female Genital Neoplasms, Female High-Intensity Focused Ultrasound Ablation Humans Leiomyoma Leiomyoma Patient Safety Uterine Neoplasms Uterine Neoplasms

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License: CC0 · commercial use OK