Effect of prostaglandin and antiprostaglandin on midcycle myometrial contractions

In: Fertility and Sterility · 2004 · vol. 82(2) , pp. 511–513 · doi:10.1016/j.fertnstert.2004.04.020 · W2162237868
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This paper investigated the impact of prostaglandins and antiprostaglandins on myometrial contractions occurring during the midcycle phase.

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Abstract

To prospectively determine the effects of prostaglandin E(2) and an antiprostaglandin, ibuprofen, on midcycle myometrial contractions, 20 healthy women underwent endovaginal ultrasound to record contractions after receiving these medications. Prostaglandin E(2) stimulated, while ibuprofen inhibited contractions, revealing the important role prostaglandins have on midcycle contractions.

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