Association between anti Mullerian hormone levels with size and bilaterality of ovarian endometrioma : a cross-sectional study

A.M.D. Rachmayana, Nurul Akmaryanti Abdullah, Eddy Hartono, Fatmawati Madya, S. Sriwijaya, Firdaus Hamid
In: Italian Journal of Gynaecology and Obstetrics · 2024 · vol. 37(01) , pp. 69 · doi:10.36129/jog.2024.181 · W4402196477
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study found no association between anti-Mullerian hormone levels and the size or bilaterality of ovarian endometriomas in 50 women.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-08 ⓘ

This cross-sectional study enrolled 50 women with presurgical ovarian endometrioma confirmed by histopathology at Wahidin Sudirohusodo Hospital (Jan–Oct 2023) and measured serum anti-Mullerian hormone (AMH) by ELISA, while endometrioma size and bilaterality were assessed by transabdominal ultrasound. AMH levels did not differ by age, menarche age, education, parity, BMI, or by whether the endometrioma was unilateral or bilateral, and tumor size was not significantly associated with AMH. Correlation analyses showed age and tumor size were negatively correlated with AMH and menarche age was positively correlated, but these associations were not statistically significant. A key limitation stated is that conclusions are limited by the relatively small sample size and the study calls for larger studies to confirm findings. This paper is centrally about endometriosis — it specifically evaluates whether serum AMH is associated with ovarian endometrioma size and bilaterality.

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Abstract

Objective.This study aims to analyze the association between anti-Mullerian hormone levels and the size and bilaterality of ovarian endometriomas. Materials and Methods.The study was conducted from January to October 2023 at Wahidin Sudirohusodo Hospital in Makassar using a cross-sectional design through consecutive sampling of ovarium endometrioma patient confirmed by histopathological examination.AMH levels were measured by ELISA technique, size and bilaterality were determined based on abdominal ultrasound examination.Results.A total of 50 women, with a mean age 32.24 0.75 years, were enrolled in the study.There was no difference in the effect of age, menarche age, education, parity, BMI, endometrioma bilaterality, or tumor size on AMH levels (p > 0.05).In the correlation test, age (r = -0.248)and tumor size (r = -0.276)were negatively correlated with AMH levels, while menarche age (r = 0.067) was positively correlated with AMH levels, but all three variables were statistically insignificant (p > 0.05). Conclusions.There was no association anti mullerian hormone level with the size and bilaterality of ovarium endometrioma.Further research is needed with a larger sample size to confirm it.

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endometrioma

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