Endotoxin aggression in the pathogenesis of chronic inflammatory diseases of small pelvis organs and infertility, or an antiendotoxin approach to their treatment

Endotoxin aggression is involved in the pathogenesis of chronic inflammatory gynecological diseases and primary and secondary female infertility. A significant (13-to 15-fold) increase in the lipopolysaccharide concentration in the blood serum is not associated with a rise in the body temperature or an increase in the titers of antibodies against Re glycolipid, which suggests chronic endotoxin aggression and endotoxin tolerance. Supplementing the conventional scheme of treatment with an antiendotoxin component increases the treatment efficiency, considerably decreases the concentration of bacterial lipopolysaccharides in the blood flow, and increases the antiendotoxin immunity. All this indicates the involvement of endotoxin aggression in the pathogenesis of the diseases under study. Similar content being viewed by others

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