Rare Broad Ligament Cavernous Hemangioma Mimicking Advanced Endometriosis: A Case Report

Cavernous hemangioma within the female genital tract is an extremely rare pathology, characterized by irregular vascular spaces containing blood or thrombus. We present a unique case of a 42-year-old primiparous woman who presented with typical endometriosis symptoms such as dysmenorrhea, dyspareunia, and heavy menstrual bleeding. The patient also experienced complex postpartum symptoms, which were misdiagnosed as cholecystitis and retained placental products. Imaging studies suggested deep infiltrative endometriosis with extraovarian endometriotic lesions. Surgical exploration revealed a hemangioma within the right anterior broad ligament alongside peritoneal endometriosis lesions. The hemangioma itself expresses estrogen and progesterone receptors in stromal cells. The presence of steroid hormone receptors strongly suggests symptom alleviation during the menstrual cycle and the postpartum period. The coexistence of cavernous hemangioma and endometriosis in the broad ligament, previously unreported, and symptomatic overlap between the two conditions complicates diagnosis and management, emphasizing the need for comprehensive evaluation integrating clinical symptoms and imaging findings. Similar content being viewed by others Data Availability If needed, we can provide further information. Code Availability Not applicable.

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There is no acknowledgment in this study. Funding This research received no specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Author information Authors and Affiliations Contributions Timur Seckin prepared, drafted, and revised the manuscript. Hakan Kula assisted with data collection, writing, manuscript preparation, and submission. Amanda Chu and Sabina Hajiyeva aided in data collection. Amanda Chu and Tamer Seckin conducted the critical review. All authors approved the submitted version and agreed to be personally accountable for their contributions, ensuring that any questions regarding the accuracy or integrity of the work are appropriately investigated and documented in the literature. Corresponding author Ethics declarations Ethics Approval Not applicable. Consent to Participate Informed consent is taken from the patient for participation and publication. Consent for Publication Informed consent is taken from the patient for participation and publication. Competing Interests The authors declare that they have no competing interests. Timur Seckin, Hakan Kula, Amanda Chu, and Sabina Hajiyeva declare they have nothing to disclose. Tamer Seckin declares that he has a leadership role with the Endometriosis Foundation of America. Attestation Statement Data regarding any of the subjects in the study has not been previously published unless specified. Data will be made available to the journal editors for review or query upon request. Additional information Publisher’s Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Rights and permissions Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. About this article Cite this article Seckin, T., Kula, H., Chu, A. et al. Rare Broad Ligament Cavernous Hemangioma Mimicking Advanced Endometriosis: A Case Report. Reprod. Sci. 31, 3351–3356 (2024). https://doi.org/10.1007/s43032-024-01675-9 Received: Accepted: Published: Version of record: Issue date: DOI: https://doi.org/10.1007/s43032-024-01675-9