Endometriosis and uterine leiomyomata with ovarian granulosa cell tumour

article OA: bronze CC0 ⤵ 4 in-corpus citations
AI-generated summary by gemini-2.5-flash-lite, 2026-06-13

This report details a patient with endometriosis and uterine leiomyomata complicated by an ovarian granulosa cell tumor, suggesting a link between estrogen-secreting neoplasms and the development of these conditions.

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Abstract

We report the first known case of right endometrial cyst and multiple uterine leiomyomata complicated by an ovarian granulosa cell tumour of adult type. A 42 year old woman had an adult type left granulosa cell tumour. Laparoscopy 13 years earlier had revealed a small endometrial implant on the peritoneum, without uterine leiomyomata or bilateral ovarian tumours. Findings in this case suggest that the aetiology of endometriosis and uterine leiomyomata are related to the presence of an oestrogen-secreting neoplasm and that the presence of a state of hyperoestrogenaemia due to granulosa cell tumour over several years might have stimulated the development of endometriosis and leiomyomata.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Granulosa Cell Tumor Granulosa Cell Tumor Leiomyomatosis Leiomyomatosis Neoplasms, Multiple Primary Ovarian Neoplasms Ovarian Neoplasms Uterine Neoplasms Uterine Neoplasms Adult Endometriosis Endometriosis Estrogens Estrogens Female Granulosa Cell Tumor Granulosa Cell Tumor Humans

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Cited by (4)

References (9)

Cited by (4)

Source provenance

europepmc
last seen: 2026-09-13T09:25:22.628771+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:10:40.754221+00:00
License: CC0 · commercial use OK