Postmenopausal Deep Infiltrating Endometriosis of the Colon: Rare Location and Novel Medical Therapy

Benjamin Snyder, Joseph Beets, Joseph W Beets, Bruce A Lessey, Samuel R W Horton, Gary A Abrams
Case reports in gastrointestinal medicine · 2018 · vol. 2018 , pp. 1–5 · doi:10.1155/2018/9587536 · PMID:29666722 · PMC5832128 · W2790662974
article OA: gold CC0 ⤵ 8 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

A postmenopausal patient with deep infiltrating colon endometriosis, a rare hepatic flexure location presenting as iron deficiency anemia, was successfully treated with conjugated estrogen-bazedoxifene instead of surgery.

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Abstract

We report an uncommon case of deep infiltrating endometriosis of the colon presenting as iron deficiency anemia nine years after hysterectomy with bilateral salpingo-oophorectomy. The endometrial implant was found at the hepatic flexure, an exceedingly rare location for endometriosis invasion with no cases distinctly reported in the literature. Additionally, the presentation of gastrointestinal endometriosis as iron deficiency anemia is not well documented in the literature. Instead of surgery, we prescribed a novel medical therapeutic approach using conjugated estrogen-bazedoxifene to antagonize the proliferative effects of estrogen on endometrial tissue. After five months of therapy and repeat colonoscopy, no evidence of endometrial tissue remained in the hepatic flexure.

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Condition tags

endometriosisdie_deep_infiltrating

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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