Correlation of preoperative biomarkers with severity of adhesion in endometriosis

Yoojung Lee, Lee Y, Yaeheun Lee, Seungho Lee, Lee S, Seung‐Ho Lee, Sunyong Jung, Jung S, Seungjoo Chon, Chon S
Journal of gynecology obstetrics and human reproduction · 2019 · vol. 49(1) , pp. 101637 · doi:10.1016/j.jogoh.2019.101637 · PMID:31520750 · W2972679477
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This study correlated preoperative biomarkers with the severity of adhesion in endometriosis patients.

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Abstract

This study was undertaken to evaluate the correlation between preoperative Serum markers and pelvic adhesions in endometriosis patients and to explore the markers' clinical value for outcome prediction. Preoperative blood Serum and CA 125 results were obtained and pelvic adhesion scores were calculated. The patient group with adhesion scores less than 28 points was defined as the mild adhesion group, and those with a score of 28 or more were members of the severe adhesion group. The CA 125 level was significantly higher in the severe adhesion group than in the mild adhesion group. The CA 125 level, size of the largest cyst, and WBC count were associated with the level of pelvic adhesion. Adhesion scores were significantly higher in the CA 125 ≥ 35 U/mL group than in the CA 125 < 35 U/mL group. Patients with a preoperative CA 125 level higher than 35 U/mL are at high risk for pelvic adhesion.

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Condition tags

endometriosis

MeSH descriptors

Biomarkers CA-125 Antigen Endometriosis Adult Biomarkers CA-125 Antigen Cysts Cysts Cysts Endometriosis Endometriosis Female Humans Leukocyte Count Middle Aged Pelvis Preoperative Period Prognosis Retrospective Studies ROC Curve

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (27)

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