Urinary Endometriosis Misdiagnosed as Ureteral Malignant Tumor by PET/CT: A Case Study

Haoyu Zhu, Zhu HY, Hao-Yu Zhu, Cheng Y, You Cheng, Si-Yun Wang, Siyun Wang, Wang SY, Dan Shao, Shao D
Clinical nuclear medicine · 2024 · vol. 49(3) , pp. e129–e130 · doi:10.1097/rlu.0000000000005045 · PMID:38271236 · W4391218144
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A 47-year-old woman's ureteral nodule, initially diagnosed as a malignant tumor by PET/CT, was pathologically confirmed as endometriosis.

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This case report describes a patient with urinary endometriosis who was initially misdiagnosed as having a ureteral malignant tumor based on findings from positron emission tomography/computed tomography imaging. The authors highlight that the metabolic activity and morphological features observed in the PET/CT scan closely mimicked those of malignancy, leading to diagnostic confusion before histopathological confirmation clarified the benign nature of the lesion. This instance underscores the potential for imaging modalities to yield false-positive results for cancer when evaluating patients with extragenital endometriotic implants. Relevance to endometriosis: listed as a clinical presentation involving urinary tract involvement, though the paper's main focus is the diagnostic challenge posed by PET/CT imaging.

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Abstract

Endometriosis is a chronic inflammatory estrogen-dependent benign disease. It is defined as the endometrium growing outside the uterine cavity and the myometrium. It usually has low FDG uptake but rarely occurs in the ureters. We reported a case of a 47-year-old woman's left ureteral nodule originally misdiagnosed as a ureteral malignant tumor by PET/CT and finally pathologically confirmed as endometriosis.
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From the ∗Southern Medical University †Department of Nuclear Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China. Received for publication September 9, 2023; revision accepted November 14, 2023. H.-Y.Z. and Y.C. contributed equally to this work. Conflicts of interest and sources of funding: none declared. This work was supported by the National Natural Science Foundation of China-Youth Science Foundation (82302259). Correspondence to: Si-Yun Wang, MD, PhD, Department of PET Center, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Room 515, 5/F, Weilun Bldg, 106 Zhongshan Er Rd, Guangzhou 510080, Guangdong, China. E-mail: [email protected]; or Dan Shao, MD, PhD, Department of PET Center, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Room 526, 5/F, Weilun Bldg, 106 Zhongshan Er Rd, Guangzhou 510080, Guangdong, China. E-mail: [email protected].

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis

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