Research Progress on the Treatment of Ovarian Endometrioma

珊 卢
In: Advances in Clinical Medicine · 2025 · vol. 15(05) , pp. 1979–1986 · doi:10.12677/acm.2025.1551582 · W4410781610
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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

This review discusses traditional drug and surgical treatments, traditional Chinese medicine, and emerging interventional therapies for ovarian endometrioma, highlighting potential alternative approaches and ongoing research.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-06 ⓘ

This paper is a narrative review of research progress on treatments for ovarian endometrioma, describing that it affects women of reproductive age and commonly presents with pelvic pain, dysmenorrhea, abdominal mass, and infertility, and summarizes high-level evidence for medication, surgery, interventional approaches, and traditional Chinese medicine. It reports that NSAIDs mainly relieve pain without treating the lesion, oral contraceptives and progestins (especially dienogest) can reduce endometrioma size and pain, GnRH agonists shrink lesions but have long-term low-estrogen adverse effects, and exploratory GnRH antagonists (e.g., elagolix, relugolix, linzagolix) show promising pain control with potential bone-sparing considerations; it also notes limitations that many mechanistic or interventional studies require more large, prospective, multicenter clinical validation. For larger cysts or when medical therapy fails, it states laparoscopic cystectomy is considered the standard with better outcomes than open surgery but with recurrence and possible ovarian tissue injury, while ultrasound-guided puncture plus sclerotherapy is presented as a less invasive alternative, though evidence is often retrospective, small, and lacks standardized sclerotherapy dosing parameters. Relevance to endometriosis: this review centers on ovarian endometrioma as a common endometriosis subtype and summarizes drug, surgical, interventional, and TCM approaches specifically for it.

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Abstract

卵巢子宫内膜异位囊肿是子宫内膜异位症的一种常见类型，临床以下腹疼痛，痛经，腹部包块，不孕症状为主，主要发生在育龄期妇女。对于卵巢子宫内膜异位囊肿，传统治疗主要包括药物治疗和手术治疗，中医方面也展示了许多有效的治疗方法，近年来介入治疗在卵巢子宫内膜异位囊肿方面的应用也显示出较好的治疗效果，有望成为治疗卵巢子宫内膜异位囊肿的替代方式，还有许多尚在探索中的治疗方式以期能取得更好的治疗效果。Ovarian endometrioma is a common type of endometriosis, clinical symptoms mainly include the hypogastralgia, dysmenorrhea, abdominal mass and infertility, mainly occurring in women of childbearing age. For ovarian endometrioma, traditional therapy mainly includes drug therapy and surgical therapy, traditional Chinese medicine also has a positive impact. In recent years, the application of interventional therapy in ovarian endometrioma has also shown good results, expected to be an alternative therapy of ovarian endometrioma. There are many other treatments that are still being explored in order to achieve better therapeutic results.

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Condition tags

endometriosisendometriomadysmenorrheainfertility

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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last seen: 2026-06-10T17:14:06.276822+00:00
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