Progesterone receptor modulators in gynaecological practice

Julia Wilkens, Hilary Critchley
In: Journal of Family Planning and Reproductive Health Care · 2010 · vol. 36(2) , pp. 87–92 · doi:10.1783/147118910791069178 · PMID:20406552 · W2083785155
review OA: bronze CC0 ⤵ 3 in-corpus citations
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This review examines progesterone receptor modulators (PRMs), detailing their discovery based on an unexpected antiproliferative effect on the endometrium and their current applications in gynecology.

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Abstract

The discovery of the endometrial antiproliferative effect of PRMs was an important milestone in their development. It was also unexpected, as compounds on July 14,

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