Endometriosis related to infertility

Brosens I, I Brosens, Ivo Brosens
Current opinion in obstetrics & gynecology · 1991 · vol. 3(2) , pp. 205–210 · doi:10.1097/00001703-199104000-00007 · PMID:1912352 · W2002424361
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-14 ⓘ

Endometriosis activity, not just its presence, is critical for diagnosing infertility in minimal/mild stages, and treatment should focus on neutralizing its activity rather than eliminating implants.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-08-25 · read from full text ⓘ

This review examines the complex relationship between endometriosis and female infertility, arguing that the mere presence of lesions does not automatically constitute a cause for sterility or a justification for medical intervention. The author emphasizes that for minimal or mild stages, clinical diagnosis should prioritize the biological activity of the disease rather than its physical existence. Consequently, the primary goal of treatment is identified as the inactivation or neutralization of this activity instead of the complete surgical elimination of implants. This paper is centrally about endometriosis — specifically addressing its role as a factor in infertility and the criteria for diagnosing active disease versus simple lesion presence.

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Abstract

Endometriosis is a disease affecting fertility in many women. However, the mere presence of what is defined as endometriosis cannot be accepted per se as a cause of infertility or an indication for therapy. In the minimal or mild stage the activity rather than the presence should be the criterion for diagnosis as a disease. It is also clear that the endpoint of treatment of endometriosis in infertility is not the elimination of the implants but rather the inactivation or neutralization of its activity.
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Article: PDF Only Endometriosis related to infertility - Ivo Brosens Current Opinion in Obstetrics & Gynecology 3(2):p 205-210, April 1991. Endometriosis is a disease affecting fertility in many women. However, the mere presence of what is defined as endometriosis cannot be accepted per se as a cause of infertility or an indication for therapy. In the minimal or mild stage the activity rather than the presence should be the criterion for diagnosis as a disease. It is also clear that the endpoint of treatment of endometriosis in infertility is not the elimination of the implants but rather the inactivation or neutralization of its activity. Copyright © Copyright © 1991 YEAR Wolters Kluwer Health, Inc. All rights reserved.

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Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Infertility, Female Pelvic Neoplasms Endometriosis Endometriosis Endometriosis Female Humans Infertility, Female Pelvic Neoplasms Pelvic Neoplasms Pelvic Neoplasms Pregnancy

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License: CC0 · commercial use OK