Use of antidepressants in the management of women with chronic pelvic pain

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This paper explores the utilization of antidepressants for managing chronic pelvic pain in women.

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Abstract

Despite a lack of formal evidence for the efficacy of antidepressants in the treatment of CPP, several lines of evidence suggest that they may play an increasingly important role in the treatment of this disorder. Although best combined as part of a multimodal treatment package that includes psychotherapy, behavior change, and physical activation, they appear to have promise for at least a subgroup of women with chronic pain. The relative safety of these medications and the high prevalence of major depression in this population of patients make the routine empirical trial of these medications a desirable, cost- and time-effective strategy in the treatment of this disorder.

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Condition tags

chronic_pelvic_pain

MeSH descriptors

Antidepressive Agents Pelvic Pain Antidepressive Agents Chronic Disease Female Humans Nociceptors Nociceptors Pelvic Pain Pelvic Pain Pelvic Pain

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References (21)

Cited by (23)

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openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:59:20.378211+00:00
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License: CC0 · commercial use OK