Defying Occam's Razor: Colonic Luminal Endometriosis in an Adolescent With Crohn's Disease

Lauren J. Klein, Avani A. Pendse, Pendse AA, Rhonda Mittenzwei, Mittenzwei R, Noel R, Richard Noel, Richard J. Noel
The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2019 · vol. 66(3) , pp. 375–377 · doi:10.1016/j.jadohealth.2019.09.018 · PMID:31771925 · W2990820257
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This case report describes colonic luminal endometriosis, a rare condition, found in an adolescent patient diagnosed with Crohn's disease.

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Abstract

Abdominal pain is a common symptom in Crohn's disease, presumably associated with mucosal inflammation and/or luminal stenosis. However, pain is not specific to Crohn's disease, and other etiologies should be considered, particularly gynecologic pathology in an adolescent female. We present an unusual case of endometrial tissue found in the colonic polyp of an adolescent with known Crohn's disease and abdominal pain. Histologic analysis differentiated endometriosis from active inflammation secondary to Crohn's disease. Endometriosis and Crohn's disease are both classified as chronic inflammatory disorders. It remains unclear whether overlapping etiological factors exist for the two disorders. There is a paucity of data on comanagement of endometriosis and inflammatory bowel disease, especially in adolescents. Given the finding of endometriosis in the colonic polyp was unanticipated, this case also reinforces the merits of endoscopic staging of disease whenever significant changes in therapy are considered.

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Condition tags

endometriosis

MeSH descriptors

Abdominal Pain Colonic Polyps Colonoscopy Crohn Disease Endometriosis Abdominal Pain Abdominal Pain Adolescent Adolescent Biopsy Biopsy Colonic Polyps Colonic Polyps Colonic Polyps Colonoscopy Colonoscopy Crohn Disease Crohn Disease Diagnosis, Differential Diagnosis, Differential

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

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