ADIPONECTIN SERUM LEVEL DIFFERENCE IN WOMEN WITH ENDOMETRIOTIC AND NON-ENDOMETRIOTIC CYSTS

In: Journal Of Medicine & Health · 2015 · vol. 1(2) · doi:10.28932/jmh.v1i2.512 · W2792293081
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This study found lower serum adiponectin levels in women with endometriotic cysts compared to women with non-endometriotic cysts, with no correlation to endometriosis stage.

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This analytical cross-sectional study compared serum adiponectin levels between 25 women with endometriotic cysts and 25 women with non-endometriotic cysts undergoing laparoscopic or laparotomy surgery, and also assessed relationships with endometriosis stage. After statistical comparison, the groups did not differ significantly in age or BMI, but adiponectin levels were significantly lower in the endometriotic cyst group (mean 3.91) than in the non-endometriotic cyst group (mean 8.59). The paper found no significant differences in adiponectin levels between stage III (mean 4.24) and stage IV endometriosis (mean 3.54). This paper is centrally about endometriosis — it measures serum adiponectin differences between women with endometriotic versus non-endometriotic cysts and examines whether adiponectin varies by endometriosis stage.

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Abstract

Endometriosis is an estrogen-dependent disease. Low levels of adiponectin resulted in an increased free estrogen levels and the inability to inhibit angiogenesis and the inflammatory process resulting in the development of increasingly severe endometriosis.This study is aimed to determine the differences in serum adiponectin levels in patient with nonendometriotic cyst with endometriosis cyst and its relationship with endometriosis stages. This is an analytical comparative study with cross-sectional method in group of women with endometriotic cyst (n=25) and women with non-endometriotic cysts (n=25), performed either laparoscopic or laparotomy surgery. The serum levels of adiponectin in both groups then compared with statistical analysis.The results showed there were no significant differences (p>0,05) on the characteristics of the study subjects in terms of age (p=0.994) and BMI (p=0.27). Significant differences of adiponectin levels were found between endometriotic patient group (mean=3.91) and nonendometriotic patients group (mean=8.59). There were no significant differences of adiponectin level in stages III endometriosis (mean = 4.24) and stage IV endometriosis (mean = 3.54).It is concluded that serum adiponectin levels in patients with endometriosis is lower than patient with non-endometriotic cyst. There is no relationship between adiponectin levels with endometriosis stage. Keywords: adiponectin, endometriotic cyst, non-endometriotic cyst, endometriosis stage
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ADIPONECTIN SERUM LEVEL DIFFERENCE IN WOMEN WITH ENDOMETRIOTIC AND NON-ENDOMETRIOTIC CYSTS DOI: https://doi.org/10.28932/jmh.v1i2.512Abstract Endometriosis is an estrogen-dependent disease. Low levels of adiponectin resulted in an increased free estrogen levels and the inability to inhibit angiogenesis and the inflammatory process resulting in the development of increasingly severe endometriosis.This study is aimed to determine the differences in serum adiponectin levels in patient with nonendometriotic cyst with endometriosis cyst and its relationship with endometriosis stages. This is an analytical comparative study with cross-sectional method in group of women with endometriotic cyst (n=25) and women with non-endometriotic cysts (n=25), performed either laparoscopic or laparotomy surgery. The serum levels of adiponectin in both groups then compared with statistical analysis.The results showed there were no significant differences (p>0,05) on the characteristics of the study subjects in terms of age (p=0.994) and BMI (p=0.27). Significant differences of adiponectin levels were found between endometriotic patient group (mean=3.91) and nonendometriotic patients group (mean=8.59). There were no significant differences of adiponectin level in stages III endometriosis (mean = 4.24) and stage IV endometriosis (mean = 3.54).It is concluded that serum adiponectin levels in patients with endometriosis is lower than patient with non-endometriotic cyst. There is no relationship between adiponectin levels with endometriosis stage. Keywords: adiponectin, endometriotic cyst, non-endometriotic cyst, endometriosis stageDownloads Download data is not yet available. Downloads Published 2015-08-31 How to Cite 1. Anwar R, Fahdiansyah F. ADIPONECTIN SERUM LEVEL DIFFERENCE IN WOMEN WITH ENDOMETRIOTIC AND NON-ENDOMETRIOTIC CYSTS. J. Med. Health [Internet]. 2015Aug.31 [cited 2026Jun.8];1(2). Available from: https://journal.maranatha.edu/index.php/jmh/article/view/512 Issue Section Articles License Authors who publish with this journal agree to the following terms: - Authors retain the copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. - Authors are able to enter into separate, additional contractual arrangements for the nonexclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal. This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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