Clinical value of preoperative serum calcium level in predicting deep infiltrative endometriosis among ovarian endometrioma
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This study found that lower albumin-adjusted serum calcium levels were associated with deep infiltrative endometriosis in patients with ovarian endometrioma.
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Abstract
OBJECTIVE: To evaluate preoperative serum calcium levels and their association with deep infiltrating endometriosis (DIE) in ovarian endometrioma. DESIGN: A retrospective, observational cohort study. PARTICIPANTS: A total of 2,557 women who underwent surgery for benign ovarian tumors were initially enrolled. Of these, 987 were pathologically confirmed to have endometriosis, while the remaining 1570 did not. RESULT: =0.047). CONCLUSION: Albumin-adjusted calcium level was lower in patients diagnosed with EM compared to those with other benign ovarian tumors. The combined use of albumin-adjusted calcium and CA125 may potentially offer enhanced diagnostic utility for EM, though further validation is required. Moreover, a lower serum level of albumin-adjusted calcium was associated with the presence of DIE among EM patients.
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- europepmc
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