Abstract Purpose To quantify how anatomical compartment involvement—derived from standardised intraoperative mapping at 29 pelvic sites—predicts the need for segmental rectal resection in deep infiltrating endometriosis (DIE). We also c…
OBJECTIVE: This study aimed to provide guidance for couples in dietary adjustments to optimize trace element concentrations for improved fertility and to offer a reference for formulating precise reproductive health policies. DESIGN: In th…
The potential bidirectional causal relationship between endometriosis and serum 25-hydroxyvitamin D has been previously investigated. Nevertheless, the results could be impacted by confounding factors and reverse causality because of the na…
We report a rare case of sporadic cervical clear cell adenocarcinoma (CCAC) in a 46-year-old perimenopausal woman without the classic risk factors of in utero diethylstilbestrol (DES) exposure or high-risk human papillomavirus (HPV) infecti…
[This corrects the article DOI: 10.3389/fendo.2025.1687765.].
PURPOSE: To ascertain whether female factors uniformly impact the entire spectrum of early embryo development during in vitro fertilization (IVF) treatments or if their influence is confined to specific stages. METHODS: A retrospective obs…
BACKGROUND: Endometrial thickness (EMT) is widely monitored in assisted reproductive technology as a marker of implantation potential, yet its precise association with pregnancy and perinatal outcomes in frozen embryo transfer (FET) cycles …
BACKGROUND: The impact of changes in estradiol (E2) levels prior to human chorionic gonadotropin (hCG) administration during controlled ovarian hyperstimulation (COH) on pregnancy and live birth outcomes remains poorly understood. OBJECTIV…
BACKGROUND: Although the cardiometabolic index (CMI) has gained recognition as a new tool for evaluating metabolic health, the relationship between CMI and cardiovascular disease (CVD) remains unclear. This research sought to explore the po…
Traumatic brain injury (TBI) is a recognized global public health problem. However, there are still limitations in the available therapeutic approaches and a lack of clinically effective drugs. Therefore, an in-depth exploration of the seco…
OBJECTIVE: To evaluate preoperative serum calcium levels and their association with deep infiltrating endometriosis (DIE) in ovarian endometrioma. DESIGN: A retrospective, observational cohort study. PARTICIPANTS: A total of 2,557 women w…
OBJECTIVE: To investigate the correlation between preoperative pathologic characteristics and the risk of postoperative recurrence in endometriosis (EMs) patients, and to develop a clinical predictive model. METHODS: A retrospective analys…
AIM: Infertility is a growing global health issue affecting millions worldwide. While endometriosis, polycystic ovarian syndrome (PCOS) and unexplained infertility are recognized as the major contributors, their specific burden and impact o…
PURPOSE: Investigating whether increasing the dose of gonadotropins (Gn) in the second in vitro fertilization (IVF) cycle using the antagonist protocol could improve the cumulative live birth rate (CLBR) in POSEIDON Groups 1 and 2. METHODS…
BACKGROUND: This study aims to evaluate the impact of endometriotic cysts and prior ovarian endometriotic cystectomy on ovarian reserve function in women with endometriosis undergoing assisted reproductive technology. METHODS: In this retr…
BACKGROUND: Successful implantation is dependent on a synchronous dialogue between several proteins that act to control cellular dynamics including actin and microtubule reorganisation and cell motility. An impaired crosstalk can lead to co…
Rationale: Endometriosis, characterized by the presence of ectopic endometrial-like tissue, is a common chronic inflammatory disorder in gynecology. However, current treatments, including surgery and hormone therapy, often yield suboptimal …
OBJECTIVE: We aimed to analyze the correlation between the neutrophil-to-lymphocyte ratio (NLR), and the treatment outcomes for infertile women after in vitro fertilization (IVF) using embryo transfer technology. METHODS: This retrospectiv…
Lymph node metastasis (LNM) confers significant treatment failure and adverse clinical outcomes in cervical cancer (CCa). However, large unknown lies in the mechanisms underlying LNM in CCa. In this study, we discovered that PRDX3 is elevat…
This study aimed to identify risk and protective factors for postoperative recurrence of deep infiltrating endometriosis (DIE). We analyzed 320 patients undergoing laparoscopic excision with ≥ 6 years follow-up at the First Affiliated Hospi…
Innate lymphoid cells (ILCs) are a newly discovered subset of immune cells that are responsible for regulation of the immune microenvironment. In particular, the ILC categories ILC2s and regulatory ILCs (ILCregs) are associated with immunos…
Central adiposity, measured by waist-to-hip ratio (WHR), is a modifiable risk factor for female infertility, yet its causal role remain underexplored. Combining observational data from National Health and Nutrition Examination Survey (N = 1…
BACKGROUND: Imbalances in alkali elements (AEs) and alkaline earth elements (AEEs) cause reproductive disorders. However, it remains unclear whether AEs/AEEs in follicular fluid have a relationship with the serious reproductive disorder kno…