Adenomyosis of the uterus: an enigma.

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Adenomyosis, a poorly understood uterine condition, is associated with myometrial muscle pattern accentuation, multiparity, and endometrial hyperplasia, affecting women in their fourth and fifth decades.

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Abstract

Adenomyosis has been an entity of some interest for many years, but little is known today of its pathogenesis. There is almost universal agreement that it is associated with an accentuation of the myometrial muscle pattern, multiparity, and endometrial hyperplasia. Some authors suggest that the myometrium is vulnerable to invasion by endometrial hyperplasia. Others postulate that the myometrium is vulnerable to invasion by endometrial glands because of the absence of a basement membrane. Women in the fourth and fifth decades of life are most commonly afflicted. Preoperative diagnosis is not common.
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Abstract Adenomyosis has been an entity of some interest for many years, but little is known today of its pathogenesis. There is almost universal agreement that it is associated with an accentuation of the myometrial muscle pattern, multiparity, and endometrial hyperplasia. Some authors suggest that the myometrium is vulnerable to invasion by endometrial hyperplasia. Others postulate that the myometrium is vulnerable to invasion by endometrial glands because of the absence of a basement membrane. Women in the fourth and fifth decades of life are most commonly afflicted. Preoperative diagnosis is not common. Full text PDFSelected References These references are in PubMed. This may not be the complete list of references from this article. - Huseby R. A., Thurlow S. Effects of prenatal exposure of mice to "low-dose" diethylstilbestrol and the development of adenomyosis associated with evidence of hyperprolactinemia. Am J Obstet Gynecol. 1982 Dec 15;144(8):939–949. doi: 10.1016/0002-9378(82)90189-2. [DOI] [PubMed] [Google Scholar]

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Condition tags

endometriosisadenomyosis

MeSH descriptors

Endometriosis Uterine Neoplasms Adult Aged Endometriosis Endometriosis Female Humans Hysterectomy Middle Aged United States Uterine Neoplasms Uterine Neoplasms

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europepmc
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