Functional association of interleukin-18 gene –607 C/A promoter polymorphisms with endometriosis

Lokman Ayaz, Çelik SK, Sevim Çelik, Sevim Karakaş Çelik, Çayan F, Filiz Çayan, Aras-Ateş N, Nurcan Aras-Ateş, Tamer L, Lülüfer Tamer
Fertility and sterility · 2010 · vol. 95(1) , pp. 298–300 · doi:10.1016/j.fertnstert.2010.07.1046 · PMID:20797704 · W1964205019
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This study investigated the functional association between interleukin-18 gene –607 C/A promoter polymorphisms and endometriosis, revealing a significant link.

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Abstract

This study evaluated for the first time the relationship between interleukin-18 (IL-18) C607A genotypes and endometriosis in 135 women with endometriosis and 84 controls. In the study population, IL-18 -607∗A homozygote and A allele were positively correlated with the risk of developing endometriosis or the stage of endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Interleukin-18 Polymorphism, Restriction Fragment Length Adult Endometriosis Endometriosis Female Gene Frequency Genetic Predisposition to Disease Genetic Predisposition to Disease Genotype Humans Interleukin-18 Middle Aged Promoter Regions, Genetic Promoter Regions, Genetic Risk Factors

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (22)

Cited by (10)

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