Accurate Diagnosis of Sigmoid Colon Endometriosis by Immunohistochemistry and Transmission Electron Microscopy - A Case Report.
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This case report details a 38-year-old woman with sigmoid colon endometriosis causing intestinal obstruction, diagnosed postoperatively using immunohistochemistry and transmission electron microscopy to assess moderate dysplasia.
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Abstract
Endometriosis is described as the presence of functioning endometrial tissue at sites outside the uterus. Up to 15% ofwomen in their reproductive period are affected by this condition. Endometriosis is mostly foundon the uterosacral ligaments, inside the rectovaginalseptum or vagina, in the rectosigmoid area, ovarianfossa, pelvic peritoneum, ureters, and bladder, causinga distortion of the pelvic anatomy. Colonic involvement is rare but is usually found at the level of the rectum or the sigmoid colon. Acute presentation with intestinal obstruction or perforation is rare. While malignant transformation of endometrial lesions is rare, findings of dysplasia on pathology sections can give rise to questions of management. Immunohistochemistry and electron microscopy can help decision making. We present the case of a 38 year old woman with intestinal obstruction caused by sigmoid colon endometriosis with moderate dysplasia in which transmission electron microscopy was used for postoperative diagnosis. Detailed analysis of these cases, while logistically difficult, can prove useful in understanding the etiology and pathophysiology of the disease.
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Cites (4)
- Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity 1927
- EPIDEMIOLOGY OF ENDOMETRIOSIS 1997
- Risk factors associated with endometriosis: importance of study population for characterizing disease in the ENDO Study 2013
- Endometriose intestinal: uma doença benigna? 2009
Cited by (4)
- Evaluation of the SF‑36 questionnaire for assessment of the quality of life of endometriosis patients undergoing treatment: A systematic review and meta‑analysis 2021
- Endometriosis-Associated Infertility 2018
- Methods of Transvaginal Ultrasound Examination in Endometriosis 2018
- Bowel endometriosis: Report of three cases 2017
References (5)
- Endometriose intestinal: uma doença benigna? via openalex
- EPIDEMIOLOGY OF ENDOMETRIOSIS via openalex
- Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity via openalex
- Risk factors associated with endometriosis: importance of study population for characterizing disease in the ENDO Study via openalex
- W2079224311 via openalex
Cited by (4)
- Evaluation of the SF‑36 questionnaire for assessment of the quality of life of endometriosis patients undergoing treatment: A systematic review and meta‑analysis 2021
- Methods of Transvaginal Ultrasound Examination in Endometriosis 2018
- Endometriosis-Associated Infertility 2018
- Bowel endometriosis: Report of three cases 2017
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- europepmc
- last seen: 2026-06-11T06:19:48.454388+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:17:33.600579+00:00
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