Theories on Endometriosis
This paper reviews theories on endometriosis development, primarily focusing on Sampson's widely accepted hypothesis involving retrograde menstruation, viable cell presence, and implantation.
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This paper/chapter reviews multiple theories proposed to explain endometriosis development, emphasizing that Sampson’s theory is the most widely accepted. In Sampson’s framework first hypothesized in 1927, endometriosis requires three elements: retrograde menstruation, viable cells present within the retrograde menstruation, and implantation of these viable endometrial cells that continue to grow and form peritoneal lesions. The chapter presents the theory as a leading explanation but does not provide experimental results or a quantified comparison across competing theories, since it is a narrative review of ideas. This paper is centrally about endometriosis — it summarizes the major theories of endometriosis development, with special focus on Sampson’s retrograde menstruation/viable-cell implantation model.
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References (21)
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- Theories of endometriosis via openalex
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Cited by (4)
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