Intramedullary Endometriosis of the Conus Medullaris

Theodoro B Beck, Mauren Beatriz F Carbonar, Ricardo Hanel, Ricardó A. Hanel, Ricardo T Beck, Ricardo Teodoro Beck, Francisco Carbonar, Francisco Lorenzo Frazon Carbonar
Cureus · 2021 · vol. 13(4) , pp. e14581 · doi:10.7759/cureus.14581 · PMID:34036001 · PMC8136296 · W3153539955
article OA: gold CC0 ⤵ 1 in-corpus citation
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This case report and literature review describes intramedullary endometriosis of the conus medullaris, emphasizing its rarity and the importance of considering it in women with periodic neurological symptoms.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-08 ⓘ

This paper reports a case of intramedullary endometriosis (IEM) in a 30-year-old woman with sudden-onset lower limb paresthesia and neurologic examination findings of decreased sensory discrimination, with no urinary/intestinal symptoms and no menstrual-cycle relation. MRI showed a nodular intramedullary lesion in the conus medullaris at L1–L2 with heterogeneous signal and surrounding edema, and the differential diagnosis included underlying neoplasia; the mass was surgically removed and diagnosis was confirmed by histology and immunohistochemistry (CD10, PAX8, and estrogen receptors). The patient achieved complete bilateral improvement of sensory and motor deficits but remained on hormonal therapy (goserelin) for one year, and the authors highlight that the uniqueness of the case includes sudden rather than chronic symptoms, absence of hematoma, and delayed etiologic diagnosis pending surgery. This paper is centrally about endometriosis — it documents intramedullary endometriosis of the conus medullaris (intraspinal endometriosis).

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Abstract

Endometriosis (EM) is a common gynecological disease characterized by endometrial-like tissue outside the uterine cavity. We report a case of intramedullary EM, a rare condition with only seven similar cases reported until today. MRI showed a mass-like lesion within the spinal canal at the L1-L2 levels and the histological and immunohistochemical features were characteristic of intraspinal endometriosis (IEM). A review of the relevant literature and a comparison between our case and seven other similar cases were made. Intraspinal EM must be recognized as a potential cause of periodic neurological signs and symptoms in young and middle-aged women. Timely intervention and appropriate management can result in control of the disease and an improvement in neurological functions.

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Condition tags

endometriosis

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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