Approaches to the replacement of ethinylestradiol by natural 17β-estradiol in combined oral contraceptives
review
OA: closed
CC0
⤵ 20 in-corpus citations
Limited metadata. Only one source feed has indexed
this record so far — no abstract, full text, or open-access copy is
available through Endo Lab. The
publisher's page (linked below)
is the canonical location for the actual content. If you have institutional
access, use "Find at my library".
AI-generated summary
This paper explores the feasibility of substituting ethinylestradiol with natural 17β-estradiol in combined oral contraceptives due to concerns about ethinylestradiol's safety profile.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
My notes (saved in your browser only)
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (40)
- Comparative Pharmacology of Newer Progestogens via openalex
- Der Einfluß von Dienogest auf die Ovulation junger Frauen und auf weitere ausgewählte endokrinologische Parameter via openalex
- Modulation of ovarian function by an oral contraceptive containing 30 μg ethinyl estradiol in combination with 2.00 mg dienogest via openalex
- doi:10.1016/0010-7824(95)00271-5 via openalex
- doi:10.1055/s-2008-1026392 via openalex
- doi:10.1016/s0140-6736(77)90888-1 via openalex
- doi:10.1016/0002-9378(88)90203-7 via openalex
- W110740893 via openalex
- W140490418 via openalex
- doi:10.1016/0960-0760(95)00214-6 via openalex
- W594682528 via openalex
- doi:10.1007/978-1-4613-2241-2_9 via openalex
- doi:10.1016/s0140-6736(95)91928-7 via openalex
- doi:10.1016/s0010-7824(96)00201-6 via openalex
- doi:10.1016/s0140-6736(95)91927-9 via openalex
- doi:10.1358/dof.1996.021.01.413907 via openalex
- doi:10.1016/s0140-6736(79)91525-3 via openalex
- doi:10.1055/s-0038-1646528 via openalex
- doi:10.1016/s0140-6736(95)91926-0 via openalex
- doi:10.3109/00365518409083621 via openalex
- W2275376451 via openalex
- W2278104485 via openalex
- W2282378924 via openalex
- W2300692921 via openalex
- W2394932821 via openalex
- W2400296091 via openalex
- W6601802762 via openalex
- W6796651853 via openalex
- W6796849299 via openalex
- doi:10.1016/0378-5122(94)00856-3 via openalex
- doi:10.1136/bmj.312.7023.83 via openalex
- doi:10.1016/0010-7824(80)90010-4 via openalex
- doi:10.1016/s0015-0282(16)56210-4 via openalex
- doi:10.1016/s0002-9378(94)05011-8 via openalex
- doi:10.1080/00365518409083621 via openalex
- doi:10.1016/0020-7292(96)89711-6 via openalex
- doi:10.1016/s0140-6736(05)64008-1 via openalex
- doi:10.1016/0960-0760(94)90146-5 via openalex
- doi:10.1002/pros.2990140410 via openalex
- doi:10.1159/000181445 via openalex
Cited by (20)
- Comparative study on the effects of combined oral contraceptives and dienogest in women with endometriosis‑associated chronic pelvic pain 2024
- Pharmacodynamics of combined estrogen-progestin oral contraceptives: 2. effects on hemostasis 2017
- Noncontraceptive Benefits of 17β-Estradiol COCs During Adolescence 2014
- Comparison of the pharmacologic and clinical profiles of new combined oral contraceptives containing estradiol 2013
- An overview of the development of combined oral contraceptives containing estradiol: focus on estradiol valerate/dienogest 2012
- Treatment of Heavy Menstrual Bleeding with the Estradiol Valerate and Dienogest Oral Contraceptive Pill 2012
- New developments in oral contraception: clinical utility of estradiol valerate/dienogest (Natazia®) for contraception and for treatment of heavy menstrual bleeding: patient considerations 2012
- Hemostatic Effects of a Novel Estradiol-Based Oral Contraceptive 2011
- Estradiol Valerate and Dienogest: A Novel Four-Phasic Oral Contraceptive Pill Effective for Pregnancy Prevention and Treatment of Heavy Menstrual Bleeding 2011
- Hemostatic Effects of a Novel Estradiol-Based Oral Contraceptive 2011
- Estradiol Valerate/Dienogest: A Novel Combined Oral Contraceptive 2011
- Metabolic and Haemostatic Effects of Estradiol Valerate/Dienogest, a Novel Oral Contraceptive 2011
- Progestins for the Treatment of Endometriosis: An Update: 2010
- Progestins for the Treatment of Endometriosis: An Update 2010
- Pharmacokinetics of an oral contraceptive containing oestradiol valerate and dienogest 2009
- Bleeding pattern and cycle control with an estradiol-based oral contraceptive: a seven-cycle, randomized comparative trial of estradiol valerate/dienogest and ethinyl estradiol/levonorgestrel 2009
- Review of clinical experience with estradiol in combined oral contraceptives 2009
- Efficacy and safety of a novel oral contraceptive based on oestradiol (oestradiol valerate/dienogest): A Phase III trial 2009
- Original research article Ovulation inhibition with four variations of a four-phasic estradiol valerate/dienogest combined oral contraceptive: results of two prospective, randomized, open-label studies ☆,☆☆ 2008
- Ovulation inhibition with four variations of a four-phasic estradiol valerate/dienogest combined oral contraceptive: results of two prospective, randomized, open-label studies 2008
Source provenance
- openalex
- last seen: 2026-05-11T06:25:09.493344+00:00
- unpaywall
- last seen: 2026-06-02T02:00:03.124865+00:00
License: CC0
· commercial use OK