Risk factors for recurrence of ovarian endometriomas after surgical excision

Summary Ovarian endometrioma is a common form of endometriosis, which may cause infertility, dysmenorrhea and pelvic pain in women of reproductive age. Although surgery is the treatment of choice for endometriomas, recurrence poses a formidable frustration. This study investigated potential risk factors of endometriomas recurrence, aiming to better understand its pathogenesis. A total of 307 patients with endometriomas were followed up for an average of 28.6 months and the 1-, 2- and 3-year cumulative recurrence rate was 9.5%, 21.9%, and 29.2%, respectively. Twenty-one potential risk factors for endometriomas recurrence were evaluated using Cox’s proportional hazards models. Total revised American Fertility Society (rAFS) score was significantly associated with higher recurrence (OR=1.858, 95% CI=1.122–3.075, P=0.016), as well as younger age at surgery (OR=0.953, 95% CI=0.915–0.992, P=0.020). Semiradical surgical treatment was defined as surgical removal of cyst plus hysterectomy with preservation of bilateral or unilateral ovary, and was a significant factor that was associated with lower recurrence than the conservative surgery (OR=0.318, 95% CI=0.107–0.951, P=0.040). Postoperative pregnancy was favorable factors for disease recurrence (OR=0.217, 95% CI=0.102–0.460, P=0.000). The results suggest that endometrioma recurrence is inversely associated with age at surgery and postoperative pregnancy, and may correlate with total rAFS score and conservative surgery method. Similar content being viewed by others References Koninckx PR, Meuleman C, Demeyere S, et al. Suggestive evidence that pelvic endometriosis is a progressive disease, whereas deeply infiltrating endometriosis is associated with pelvic pain. Fertil Steril, 1991,55(4):759–765 Chapron C, Pietin-Vialle C, Borghese B, et al. 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Hum Reprod, 2010,25(3):665–671 Author information Authors and Affiliations Corresponding author Additional information This project was supported by the National Science Foundation for Young Scientists of China (No. 81000240). Rights and permissions About this article Cite this article Yuan, M., Wang, Ww., Li, Y. et al. Risk factors for recurrence of ovarian endometriomas after surgical excision. J. Huazhong Univ. Sci. Technol. [Med. Sci.] 34, 213–219 (2014). https://doi.org/10.1007/s11596-014-1261-9 Received: Revised: Published: Issue date: DOI: https://doi.org/10.1007/s11596-014-1261-9