{"paper_id":"45ca937f-f205-41e6-b07a-78c238f740f9","body_text":"Summary\nOvarian endometrioma is a common form of endometriosis, which may cause infertility, dysmenorrhea and pelvic pain in women of reproductive age. Although surgery is the treatment of choice for endometriomas, recurrence poses a formidable frustration. This study investigated potential risk factors of endometriomas recurrence, aiming to better understand its pathogenesis. A total of 307 patients with endometriomas were followed up for an average of 28.6 months and the 1-, 2- and 3-year cumulative recurrence rate was 9.5%, 21.9%, and 29.2%, respectively. Twenty-one potential risk factors for endometriomas recurrence were evaluated using Cox’s proportional hazards models. Total revised American Fertility Society (rAFS) score was significantly associated with higher recurrence (OR=1.858, 95% CI=1.122–3.075, P=0.016), as well as younger age at surgery (OR=0.953, 95% CI=0.915–0.992, P=0.020). Semiradical surgical treatment was defined as surgical removal of cyst plus hysterectomy with preservation of bilateral or unilateral ovary, and was a significant factor that was associated with lower recurrence than the conservative surgery (OR=0.318, 95% CI=0.107–0.951, P=0.040). Postoperative pregnancy was favorable factors for disease recurrence (OR=0.217, 95% CI=0.102–0.460, P=0.000). The results suggest that endometrioma recurrence is inversely associated with age at surgery and postoperative pregnancy, and may correlate with total rAFS score and conservative surgery method.\nSimilar content being viewed by others\nReferences\nKoninckx PR, Meuleman C, Demeyere S, et al. Suggestive evidence that pelvic endometriosis is a progressive disease, whereas deeply infiltrating endometriosis is associated with pelvic pain. Fertil Steril, 1991,55(4):759–765\nChapron C, Pietin-Vialle C, Borghese B, et al. 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Hum Reprod, 2010,25(3):665–671\nAuthor information\nAuthors and Affiliations\nCorresponding author\nAdditional information\nThis project was supported by the National Science Foundation for Young Scientists of China (No. 81000240).\nRights and permissions\nAbout this article\nCite this article\nYuan, M., Wang, Ww., Li, Y. et al. Risk factors for recurrence of ovarian endometriomas after surgical excision. J. Huazhong Univ. Sci. Technol. [Med. Sci.] 34, 213–219 (2014). https://doi.org/10.1007/s11596-014-1261-9\nReceived:\nRevised:\nPublished:\nIssue date:\nDOI: https://doi.org/10.1007/s11596-014-1261-9","source_license":"public-domain-us","license_restricted":false}