A Review on the Vitamin D and In Vitro Fertilization Outcomes

İlkay Boz, Gamze Teskereci
In: Archives of Health Science and Research · 2017 · vol. 4(3) , pp. 252–259 · doi:10.17681/hsp.283145 · W2760690818
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⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This review examines 13 studies on vitamin D's impact on in vitro fertilization outcomes, noting its association with infertility factors and the need for further research.

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Abstract

The effect on reproductive process of vitamin D is a controversial issue although the function on the bone mineralization and maintaining of the calcium-phosphorus balance of vitamin D is quite well-known. National and international studies show that vitamin D deficiency is quite common among women of reproductive age. Vitamin D with sex steroids are known to be effective in male and female reproductive processes. It supports the view that the presence of the reproductive tissue of Vitamin D receptors and enzymes that metabolize Vitamin D. In the literature, Vitamin D deficiency is associated with etiologic factors of infertility such as fibroids, endometriosis, polycystic ovary syndrome, low ovarian reserve, lower total sperm counts and testosterone levels. In this review, 13 research were achieved examining the impact on In Vitro Fertilization results of Vitamin D. In our country, it could not be reached to a study in this issue. Also, there are two systematic review in this issue. To routine monitoring of vitamin D and promoting of treatment and care in the lack of Vitamin D, large-scale, experimental and cohort studies are needed.

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endometriosisinfertility

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