Autofluoreszenz und Endometriose

In: Der Gynäkologe · 2007 · vol. 40(5) , pp. 349–355 · doi:10.1007/s00129-007-1977-8 · W407006825
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Autofluorescence laparoscopy allows for visualization of the entire extent of endometriosis, including occult and early lesions, which may impact future therapeutic strategies.

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The paper describes laparoscopic autofluorescence imaging as a method for detecting endometriosis, comparing its performance with conventional white-light laparoscopy at a high level. The authors report that autofluorescence allows visualization of the entire extent of disease, including very small or occult lesions that would otherwise be missed. They frame this as revealing “a world behind the world,” with the stated implication that earlier and more accurate diagnosis could require reconsideration of therapeutic strategies used after conventional diagnostic approaches. This paper is centrally about endometriosis — it focuses on how autofluorescence laparoscopy improves detection of occult and early endometriotic lesions.

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Zusammenfassung Verglichen mit der konventionellen Weißlichtlaparoskopie zeigt uns die Methode der Autofluoreszenzlaparoskopie, dass Endometriose viel mehr ist, als das, was uns das bloße menschliche Auge gestattet wahrzunehmen. Die Autofluoreszenz versetzt uns in die Lage, die gesamte Ausdehnung der Erkrankung zu ermessen, okkulte Formen und Frühstformen zu diagnostizieren. Eine neue Sichtweise der Endometriose erlaubt es, die Erkrankung früher und insbesondere exakter zu diagnostizieren, was uns zum Nachdenken über den Sinn unserer therapeutischen Strategien nach konventioneller Diagnostik veranlassen sollte. Abstract Laparoscopic autofluorescence imaging of endometriosis is a new method which allows us to properly detect the disease. Autofluorescence, in contrast to conventional white light laparoscopy, enables us to visualize the entire extent of disease and to recognize extremely small or occult lesions. Autofluorescence imaging in fact reveals a world behind the world, a substantial new representation of endometriosis, which will have much impact on our future therapeutic strategies. Similar content being viewed by others Literatur ASRM (1997) Classification of endometriosis. Fertil Steril 67: 817–821 Balasch J, Creus M, Fabregues et al. (1996) Visible and non-visible endometriosis at laparoscopy in fertile and infertile women and in patients with chronic pelvic pain: a prospective study. Hum Reprod 11: 387–391 Buchweitz O, Staebler A, Tio J et al. (2006) Detection of peritoneal endometriotic lesions by autofluorescence laparoscopy. Am J Obstet Gynecol 195: 949–954 Demco L (2004) Laparoscopic spectral analysis of endometriosis. J Am Assoc Gynecol Laparosc 11: 219–222 D’Hooghe TM (2003) Invisible microscopic endometriosis: how wrong is the sampson hypothesis of retrograde menstruation to explain the pathogenesis of endometriosis? Gynecol Obstet Invest 55: 61–62 Evers JL, Dunselman GA, Groothuis P (2005) Now you see them, now you don’t. Fertil Steril 84: 31–32; discussion 38–39; Review Hillemanns P, Weingandt H, Stepp H et al. (2000) Assessment of 5-aminolevulinic acid-induced porphyrin fluorescence in patients with peritoneal endometriosis. Am J Obstet Gynecol 183: 52–57 Kang SB, Chung HH, Lee HP et al. (2006) Impact of diagnostic laparoscopy on the management of chronic pelvic pain. Surg Endosc 14 Kupker W, Linde H van der, Loning M et al. (2004) Laparoscopic autofluorescence imaging of endometriosis. Fertil Steril 82: S72–S73 Malik E, Berg C, Meyhofer-Malik A et al. (2000) Fluorescence diagnosis of endometriosis using 5-aminolevulinic acid. Surg Endosc 14: 452–455 Murphy AA, Green WR, Bobbie D et al. (1986) Unsuspected endometriosis documented by scanning electronmicroscopy in visualy normal peritoneum. Fertil Steril 46: 522–524 Wagnières G, Star W, Wilson B (1998) In vivo fluorescence spectroscopy and imaging for oncological applications. Photochem Photobiol 68: 603–632 Interessenkonflikt Es besteht kein Interessenkonflikt. Der korrespondierende Autor versichert, dass keine Verbindungen mit einer Firma, deren Produkt in dem Artikel genannt ist, oder einer Firma, die ein Konkurrenzprodukt vertreibt, bestehen. Die Präsentation des Themas ist unabhängig und die Darstellung der Inhalte produktneutral. Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Küpker, W., Diedrich, K., Villena, C. et al. Autofluoreszenz und Endometriose. Gynäkologe 40, 349–355 (2007). https://doi.org/10.1007/s00129-007-1977-8 Issue date: DOI: https://doi.org/10.1007/s00129-007-1977-8

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