Presentation of Endometriosis of the Cervix in Cervical Smear: A Case Report and Review of Literature

Balachandran I, Indra Balachandran, Gerber M, Marina Gerber, Марина Гербер
Journal of lower genital tract disease · 2002 · vol. 6(3) , pp. 162–166 · doi:10.1097/00128360-200207000-00004 · PMID:17051016 · W2011748546
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

This case report describes endometriosis of the cervix identified in a cervical smear and emphasizes its consideration in differential diagnoses for atypical endometrial cells.

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This case report and literature review examines the rare presentation of cervical endometriosis as detected through exfoliative cytology in a 48-year-old woman experiencing intermenstrual spotting. The authors describe both the cytological and histological features of the condition, highlighting how endometrial cells shed into the cervix can mimic premalignant or malignant lesions. They emphasize the critical need for clinicians to consider cervical endometriosis in the differential diagnosis when encountering abnormal endometrial shedding in cycling women. This paper is centrally about endometriosis — specifically focusing on its atypical manifestation within the cervical tissue and its detection via cervical smear analysis.

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Abstract

Endometriosis of the cervix is considered a rare lesion with a predilection in women with a previous history of cervical trauma, such as biopsy, conization, or laser vaporization. Description of endometriosis of the cervix in cytological literature is equally rare with most of the published reports dealing with the role of fine-needle aspiration in diagnosis and how the atypia in cases with cervical endometriosis poses differential diagnosis for other premalignant and malignant endocervical lesions. We present here a case depicting endometriosis of the cervix in a cervical/endocervical smear from a 48-year-old female with intermenstrual spotting. The purpose of this article is 2-fold: to report a case of endometriosis of the cervix in exfoliative cytology and to review pertinent cytological literature. In this article, cytological and histological presentation of cervical endometriosis is described, and the importance of considering cervical endometriosis in the differential diagnosis when dealing with endometrial shedding that is not part of the normal physiology in a cycling woman is emphasized.
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Presentation of Endometriosis of the Cervix in Cervical Smear: A Case Report and Review of Literature - Indra Balachandran - Marina Gerber Endometriosis of the cervix is considered a rare lesion with a predilection in women with a previous history of cervical trauma, such as biopsy, conization, or laser vaporization. Description of endometriosis of the cervix in cytological literature is equally rare with most of the published reports dealing with the role of fine-needle aspiration in diagnosis and how the atypia in cases with cervical endometriosis poses differential diagnosis for other premalignant and malignant endocervical lesions. We present here a case depicting endometriosis of the cervix in a cervical/endocervical smear from a 48-year-old female with intermenstrual spotting. The purpose of this article is 2-fold: to report a case of endometriosis of the cervix in exfoliative cytology and to review pertinent cytological literature. In this article, cytological and histological presentation of cervical endometriosis is described, and the importance of considering cervical endometriosis in the differential diagnosis when dealing with endometrial shedding that is not part of the normal physiology in a cycling woman is emphasized.

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endometriosis

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