Surgical treatment of primary dysmenorrhea with laparoscopic uterine nerve ablation
Non-randomised trial
OA: closed
CC0
⤵ 98 in-corpus citations
AI-generated summary
Laparoscopic uterine nerve ablation effectively relieved menstrual pain in 81% of primary dysmenorrhea patients, with half maintaining relief at 12 months.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
With approximately 25% of dysmenorrheic patients reporting no improvement with nonsteroidal anti-inflammatory drugs, a study was devised to evaluate the effectiveness of a laparoscopic technique for the interruption of the uterosacral nerves. In a double-blind study of 21 patients with primary dysmenorrhea, 81% (9 of 11) reported significant relief from menstrual pain after the surgery. Performed as an outpatient procedure, laparoscopic uterine nerve ablation may alleviate dysmenorrheic complaints when other modalities have failed. Half the treated women reported continued relief of menstrual pain at 12 months. These results suggest that uterosacral nerve interruption may prove an effective alternative treatment for this menstrual disorder.
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood (2-hop)
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]
Cited by (50)
- Effectiveness, Safety, and Patient Satisfaction of Laparoscopic Uterosacral Nerve Ablation in Terms of Pain Relief in Women with Chronic Pelvic Pain 2025
- Uterosacral Nerve Ablation and Presacral Neurectomy in the Treatment of Chronic Pelvic Pain in Women 2019
- Laparoscopic uterosacral nerve block: A fertility preserving option in chronic pelvic pain 2019
- Therapeutic effects of traditional Chinese herbal prescriptions for primary dysmenorrhea 2018
- Paradigm Shift: The Realization of New Medical Alternatives to Surgery for Endometriosis 2016
- Treatment of pelvic pain associated with endometriosis: a committee opinion 2014
- Endometriosis - An Update 2014
- Surgical treatment of endometriosis 2011
- Is uterine retroversion and retroflexion a disease that requires surgical correction? 2010
- Laparoscopic Treatment of Pelvic Pain 2010
- Individual patient data meta-analysis of randomized evidence to assess the effectiveness of laparoscopic uterosacral nerve ablation in chronic pelvic pain 2010
- Laparoscopic uterosacral nerve ablation for alleviating chronic pelvic pain: a randomized controlled trial 2009
- Medical, surgical and alternative treatments for chronic pelvic pain in women: a descriptive review 2009
- The Management of Chronic Pelvic Pain 2008
- The Role of Laparoscopic Uterine Nerve Ablation(LUNA) and Presacral Neurectomy (PSN) of PelvicPain Management 2008
- The Role of Laparoscopic Uterine Nerve Ablation (LUNA) and Presacral Neurectomy (PSN) of Pelvic Pain Management 2008
- Treatment of pelvic pain associated with endometriosis 2008
- Pelvic denervation procedures: a current reappraisal 2008
- Histopathologic findings on uterosacral ligaments in women with chronic pelvic pain and visually normal pelvis at laparoscopy 2007
- Surgical interruption of pelvic nerve pathways in dysmenorrhea: a systematic review of effectiveness 2007
- Meta-analysis using individual patient data from randomised trials to assess the effectiveness of laparoscopic uterosacral nerve ablation in the treatment of chronic pelvic pain: a proposed protocol 2007
- Laparoscopic uterosacral nerve ablation and chronic pelvic pain 2006
- Laparoscopic uterine nerve ablation versus vaginal uterosacral ligament resection in postmenopausal women with intractable midline chronic pelvic pain: a randomized study 2006
- Treatment of pelvic pain associated with endometriosis 2006
- Chronic pelvic pain : prevalence, risk factors and laparoscopic uterosacral nerve ablation. 2006
- Management of chronic pelvic pain: evidence from randomised controlled trials 2006
- Conservative surgical management of endometriosis in women with pelvic pain 2006
- Histopathologic findings on uterosacral ligaments in women with chronic pelvic pain and visually normal pelvis at laparoscopy 2006
- Chronic pelvic pain: Aetiology and therapy 2006
- Case report: Laparoscopic resection of the cervical adenomyoma alleviated severe chronic pelvic pain 2005
- A double-blind randomised controlled trial of laparoscopic uterine nerve ablation for women with chronic pelvic pain 2004
- Surgical management of endometriosis 2004
- The role of laparoscopy in the chronic pelvic pain patient 2003
- Treatment of Endometriosis-Related Pelvic Pain 2003
- Endometriosis 2003
- Pelvic denervation surgery: what the evidence and anatomy teach us 2003
- Adolescent endometriosis 2003
- Endometriosis: treatment strategies 2003
- Laparoscopic uterosacral ligament resection for dysmenorrhea associated with endometriosis: results of a randomized, controlled trial 2003
- Nuevos conceptos en la patogénesis y tratamiento de la endometrosis asociada a dolor 2003
- Interrupción quirúrgica de las vías nerviosas en el dolor pélvico crónico 2003
- Nerve pathways surgical interruption for chronic pelvic pain 2003
- Chronic pelvic pain 2003
- Laparoscopic Surgery for Pelvic Pain 2002
- Pelvic pain scores in women without pelvic pathology 2002
- Laparoscopic uterosacral nerve ablation (LUNA) 2002
- Consensus statement for the management of chronic pelvic pain and endometriosis: proceedings of an expert-panel consensus process 2002
- INTERRUPCI"N QUIR⁄RGICA DE LAS V˝AS NERVIOSAS EN EL DOLOR P…LVICO CR"NICO NERVE PATHWAYS SURGICAL INTERRUPTION FOR CHRONIC PELVIC PAIN 2002
- A prospective, randomized, double‐blind controlled trial of laparoscopic uterine nerve ablation in the treatment of pelvic pain associated with endometriosis 2001
- Arcus taurinus: the ‘mother and father’ of all LUNAs 2001
Source provenance
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:21:33.560900+00:00
License: CC0
· commercial use OK