Fertility drugs and ovarian epithelial cancer: The endometriosis hypothesis
This paper discusses the relationship between fertility drugs and ovarian epithelial cancer, referencing studies on infertility, IVF, endometriosis, and ovarian cancer risk.
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This brief paper discusses the endometriosis hypothesis as it relates to whether fertility drugs might influence the risk of epithelial ovarian cancer. It synthesizes prior epidemiologic and biological observations about ovarian cancer risk in infertile women and after infertility treatments, and it draws on evidence suggesting a possible malignant transformation pathway from endometriosis to early epithelial ovarian cancer. The paper’s main limitation is that it is not an original empirical study and does not present new data or a systematic quantitative analysis. Relevance to endometriosis: it explicitly frames ovarian epithelial cancer risk in terms of endometriosis-driven mechanisms, citing reports of histologic transformation of benign endometriosis to early epithelial ovarian cancer, though the paper’s main focus is fertility drugs and cancer risk.
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Too few in-corpus citations on either side for a chart; here are the lists.
Cites (2)
- Histologic Transformation of Benign Endometriosis to Early Epithelial Ovarian Cancer 1996
- Pelvic macrophages in normal and infertile women: The role of patent tubes 1982
Cited by (4)
- Increased risk for ovarian cancer and borderline ovarian tumours in subfertile women with endometriosis 2013
- Hormone replacement therapy and risk of epithelial ovarian cancer 1999
- Concomitant endometriosis in malignant and borderline ovarian tumours* 2018
- Infertility as a Cancer Risk Factor – A Review 2008
References (11)
- Histologic Transformation of Benign Endometriosis to Early Epithelial Ovarian Cancer via openalex
- Pelvic macrophages in normal and infertile women: The role of patent tubes via openalex
- W1966371456 via openalex
- W1976274871 via openalex
- W2071231589 via openalex
- W2071669935 via openalex
- W2262508003 via openalex
- W2315888143 via openalex
- W343382252 via openalex
- W2735861455 via openalex
- W1788724892 via openalex
Cited by (4)
- Concomitant endometriosis in malignant and borderline ovarian tumours* 2018
- Increased risk for ovarian cancer and borderline ovarian tumours in subfertile women with endometriosis 2013
- Infertility as a Cancer Risk Factor – A Review 2008
- Hormone replacement therapy and risk of epithelial ovarian cancer 1999
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- europepmc
- last seen: 2026-06-17T06:13:18.893374+00:00
- openalex
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- pubmed
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