The treatment of endometriosis by oral progestogens

Linton Snaith, L Snaith, SNAITH L
Proceedings of the Royal Society of Medicine · 1968 · vol. 61(4) , pp. 358–360 · doi:10.1177/003591576806100419 · PMID:5653994 · PMC1902402 · W1854065162
Other OA: bronze CC0 ⤵ 7 in-corpus citations
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This study treated 41 endometriosis patients with oral progestogens, observing improvement in 22 of 28 preoperative cases and all 18 postoperative cases.

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Abstract

41 patients were treated for endometriosis with an oral progestogen in most cases norethisterone acetate. In preoperative cases treatment was administered both continously and cyclically depending upon the incursion of side effects. In 22 out of 28 women given preoperative treatment improvement was seen before laparotomy. In postoperative treatment without previous hormone therapy all 18 cases improved whether due to surgery and/or therapy. It was undetermined if the decidual reaction followed by necrosis was the effective mechanism of the progestogens.

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Condition tags

dyspareuniaendometriosis

MeSH descriptors

Endometriosis Norethindrone Progestins Adult Adult Dyspareunia Dyspareunia Dyspareunia Embryo Implantation Embryo Implantation Embryo Implantation Endometriosis Endometriosis Endometriosis Endometriosis Endometrium Endometrium Endometrium Estrogens Estrogens

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

Cited by (7)

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europepmc
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License: CC0 · commercial use OK