Müllerianosis of the Urinary Bladder: A Rare Condition Which Mimics Neoplasia

Somshukla Ghosh, Fikret Fatih Önol, Jonathan Vásquez, Jignesh Parikh
In: Cureus · 2021 · vol. 13(5) , pp. e15147 · doi:10.7759/cureus.15147 · PMID:34178484 · PMC8216577 · W3165324049
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⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This paper describes a case of cystic Müllerianosis of the urinary bladder, a rare benign condition that mimics bladder neoplasia.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 ⓘ

This paper presents a case report of cystic müllerianosis of the urinary bladder in a 31-year-old nulliparous woman with menorrhagia and pelvic pain, along with urinary frequency and dysuria during menstruation. After laparoscopic hysterectomy for presumed fibroids, a bladder nodule seen on cystoscopy was resected transurethrally, and histopathology showed a cyst lined by tubal-type epithelium with endometrial-like stroma that was immunopositive for estrogen and progesterone receptors, supporting cystic müllerianosis. The authors note that bladder müllerianosis is rare and frequently mimics neoplasia clinically and radiologically, and management guidance is limited due to small case numbers, with malignant transformation risk and surveillance intervals unclear. Relevance to endometriosis: the case involves a hormonally responsive, endometrium-like bladder lesion presenting with menstrual-associated pelvic pain and urinary symptoms, though it is not explicitly discussed as endometriosis in the paper.

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Abstract

Müllerianosis of the urinary bladder is an extremely rare, benign condition defined by the presence of at least two of the three müllerian-derived components (endosalpinx, endometrium, and endocervix) in the lamina propria and muscularis propria of the urinary bladder. It frequently mimics neoplastic condition, either malignant or benign. Here, we present a case of cystic müllerianosis of urinary bladder, which was clinically thought to be a urinary bladder neoplasm.

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