Antinocyceptive effect of oxygen therapy and hirudotherapy in rehabilitation of patients with genital endometriosis
This study found that oxygen therapy and hirudotherapy, in addition to standard treatment, significantly reduced pelvic pain in patients with genital endometriosis compared to standard treatment alone.
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The paper evaluates changes in pain in women with genital endometriosis undergoing complex rehabilitation that includes oxygen inhalation therapy and hirudotherapy (leech therapy), with the intent to target perceived mechanisms involving hypoxia, inflammatory processes, and dysfunction of neuroendocrine systems. It describes a rationale that hirudotherapy’s biologically active secretions may exert antinociceptive effects and influence hypothalamic–limbic–reticular regulation, while additional oxygenation may normalize gas exchange around endometriotic lesions. The main finding is framed as assessing the dynamics of the pain syndrome, but the provided text does not include specific outcome results, quantitative measures, or the study design details. This paper is centrally about endometriosis — it specifically assesses the antinociceptive effects of oxygen therapy and hirudotherapy in rehabilitation of patients with genital endometriosis.
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References (12)
- Endometriosis via openalex
- <p>Research on central sensitization of endometriosis-associated pain: a systematic review of the literature</p> via openalex
- Optimal Management of Endometriosis and Pain via openalex
- Progesterone and Estrogen Signaling in the Endometrium: What Goes Wrong in Endometriosis? via openalex
- The Pathogenesis of Endometriosis: Molecular and Cell Biology Insights via openalex
- W2973233041 via openalex
- W2772853757 via openalex
- W4288400169 via openalex
- W2782501586 via openalex
- W2910029530 via openalex
- W2946552980 via openalex
- W2953986304 via openalex
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- openalex
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