Endometriosis-related spontaneous hemoperitoneum in pregnancy: A case series

Luca Bazzurini, Bazzurini L, Sara Ornaghi, Elisabetta Colciago, Cristina Penati, Penati C, di Gennaro F, Filiberto di Gennaro, Passoni P, Paolo Passoni, Buda A, Alessandro Buda, Locatelli A, Anna Locatelli, Landoni F, Fabio Landoni, Patrizia Vergani, Vergani P
Journal of Obstetrics and Gynaecology Research · 2022 · vol. 49(2) , pp. 744–752 · doi:10.1111/jog.15498 · PMID:36366961 · W4308773499
Case report OA: closed CC0 ⤵ 5 in-corpus citations
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This case series describes six pregnant or postpartum women with endometriosis-related spontaneous hemoperitoneum, typically presenting with severe abdominal pain in late gestation, requiring surgery and transfusions in most cases.

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Abstract

Endometriosis can be associated with adverse pregnancy outcomes. We report six cases of endometriosis-related spontaneous hemoperitoneum diagnosed in pregnant and postpartum women over 13 years. Spontaneous hemoperitoneum in pregnancy mainly occurred in the second half of gestation. All women presented with acute abdominal pain; four of them needed an emergent surgery, two were managed expectantly. The median estimated blood loss was 4250 ml, four women required massive transfusion. Three out of six women had a known history of endometriosis, all of them had histologically confirmed endometriosis after surgery. No maternal or perinatal deaths occurred. In one case, reticence to perform a computed tomography scan led to delayed diagnosis. Since delay can lead to lethal consequences, high levels of suspicion for spontaneous hemoperitoneum should be maintained in cases of severe abdominal pain, even with a woman's negative history of endometriosis. Improved knowledge and regular interdisciplinary meetings are pivotal to ameliorate outcomes.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (18)

Cited by (5)

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