Endometriosis and Polycystic Ovarian Syndrome

In: Obstetric and Gynecological Women's Health · 2026 · pp. 219–227 · doi:10.1007/978-3-032-05381-7_18 · W7160435208
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This chapter explores the possible correlation and common pathogenetic mechanisms between endometriosis and polycystic ovary syndrome, aiming to propose joint treatment strategies for their coexistence.

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This paper/chapter discusses the relationship between endometriosis and polycystic ovarian syndrome (PCOS), framing both as estrogen-related reproductive disorders that can negatively affect fertility. It aims to highlight a possible correlation between the two conditions and to examine shared pathogenetic mechanisms, while also proposing an approach for joint treatment when both coexist. The chapter does not present new empirical data in the provided text; a key caveat is that it is positioned as summarizing and synthesizing existing knowledge rather than establishing a definitive association. Relevance to endometriosis: it is directly focused on endometriosis and PCOS, emphasizing their potential correlation and common mechanisms, while also considering fertility impacts when they coexist.

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Abstract

Endometriosis and PolyCystic Ovary Syndrome (PCOS) are both oestrogen-related diseases that often occur among women of reproductive age. Both have a negative impact on fertility. To date, there is no extensive literature on the association of endometriosis with PCOS. In this chapter, we will try to highlight the possible correlation between the two disorders, as well as to examine possible common pathogenetic mechanisms, as well as to propose a strategy for the joint treatment of the two above-mentioned disorders when they coexist. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

References

Bulun SE. Endometriosis. N Engl J Med. 2009;360:268–79. Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, Yildiz BO. The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab. 2004;89:2745–9. The Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Work-shop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004;81:19–25. Hager M, Wenzl R, Riesenhuber S, Marschalek J, Kuessel L, Mayrhofer D, Ristl R, Kurz C, Ott J. The prevalence of incidental endometriosis in women undergoing laparoscopic ovarian drilling for clomiphene-resistant polycystic ovary syndrome: a retrospective cohort study and meta-analysis. J Clin Med. 2019;8:1210–21. Burney RO. The genetics and biochemistry of endometriosis. Curr Opin Obstet Gynecol. 2013;25:280–6. Bulun SE, Yilmaz BD, Sison C, Miyazaki K, Bernardi L, Liu S, Kohlmeier A, Yin P, Milad M, Wei J. Endometriosis. Endocr Rev. 2019;40:1048–79. The Thessaloniki ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group*. Consensus on infertility treatment related to polycystic ovary syndrome. Fertil Steril. 2008;89(3):505–22. Lambrinoudaki IV, Augoulea A, Christodoulakos GE, Economou EV, Kaparos G, Kontoravdis A, Papadias C, Creatsas G. Measurable serum markers of oxidative stress response in women with endometriosis. Fertil Steril. 2009;91:46–50. Agarwal A, Aponte-Mellado A, Premkumar BJ, Shaman A, Gupta S. The effects of oxidative stress on female reproduction: a review. Reprod Biol Endocrinol. 2012;10:49–80. Murri M, Luque-Ramirez M, Insenser M, Ojeda-Ojeda M, Escobar-Morreale HF. Circulating markers of oxidative stress and polycystic ovary syndrome: a systematic review and meta-analysis. Hum Reprod Update. 2013;19:268–88. Fichera M, Török P, Tesarik J, Della Corte L, Rizzo G, Garzon S, Carlea A, Di Angelo Antonio S, Zito G, Panella MM. Vitamin D, reproductive disorders and assisted reproduction: evidence and perspectives. Int J Food Sci Nutr. 2020;71(3):276–85. https://doi.org/10.1080/09637486.2019.1661978. Guo Z, Yu Q. Role of mTOR signaling in female reproduction. Front Endocrinol. 2019;10:692. https://doi.org/10.3389/fendo.2019.00692. Vasilopoulos E, Fragkiadaki P, Kalliora C, Fragou D, Docea AO, Vakonaki E, Tsoukalas D, Calina D, Buga AM, Georgiadis G, Mamoulakis C, Makrigiannakis A, Spandidos DA, Tsatsakis A. The association of female and male infertility with telomere length (review). Int J Mol Med. 2019;44(2):375–89. https://doi.org/10.3892/ijmm.2019.4225. Koiou E, Tziomalos K, Katsikis I, Delkos D, Tsourdi EA, Panidis D. Disparate effects of pharmacotherapy on plasma plasminogen activator inhibitor-1 levels in women with the polycystic ovary syndrome. Hormones. 2013;12:559–66. Author information Authors and Affiliations Corresponding author Editor information Editors and Affiliations Rights and permissions Copyright information © 2026 Springer Nature Switzerland AG About this chapter Cite this chapter Antonakis, L.G., Adonakis, G.L. (2026). Endometriosis and Polycystic Ovarian Syndrome. In: Di Renzo, G.C. (eds) Obstetric and Gynecological Women's Health. Springer, Cham. https://doi.org/10.1007/978-3-032-05381-7_18 Download citation DOI: https://doi.org/10.1007/978-3-032-05381-7_18 Published: Publisher Name: Springer, Cham Print ISBN: 978-3-032-05380-0 Online ISBN: 978-3-032-05381-7 eBook Packages: MedicineMedicine (R0)

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endometriosis

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