Vitamin D Levels in Patients with Endometriosis Cysts

Background: Endometriosis is associated with lipid peroxidation by reactive oxygen species (ROS) which causes endometrial cell DNA damage. Vitamin D is known to have good antioxidant content, so it is thought to have the ability to inhibit proliferation, invasion and production of pro-inflammatory cytokines in endometriosis.

To analyze the differences in vitamin D levels between endometriosis cyst patients and normal women and the relationship between vitamin D levels and the size of endometriosis cysts.

Analytical observational study with cross sectional design with 60 samples consisting of 30 endometriosis cyst patients and 30 normal women. Evaluation was carried out on vitamin 25 (OH) D serum levels using the ELISA method and endometriosis cyst size. Cyst size is evaluated by assessing the largest diameter of a single endometriosis cyst assessed through an ultrasound examination by a specialist doctor.

Vitamin D levels in the endometriosis group were significantly lower than normal women (13.23 ± 5.39 ng/mL vs 15.83 ± 5.30 ng/mL; p = 0.048). Subjects with vitamin D levels 13.45 ng/mL. There was no correlation between vitamin D levels and the size of endometriosis cysts (p=0.720).

Endometriosis patients have significantly lower serum vitamin D levels than normal women (OR 4.03; CI95% 1.37-11.83). Serum vitamin D levels do not significantly correlate with endometriosis cyst size.Note: This article has supplementary file(s). Fulltext View|Download | Copyright Transfer Agreement Conflict of Interest and CTA Email colleagues | Subject | | | Type | Copyright Transfer Agreement | | Download (43KB) Indexing metadata |

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