Determine the Connection Between Endometriosis and Hypertensive Disorders During Pregnancy: A Systematic Review

Md Sayed Ali Sheikh, Ahmed Baker Alshaikh, Maged Elshamy, Umme Salma
In: Attahadi Medical Journal · 2024 · pp. 1–4 · doi:10.69667/10.69667/amj.25101 · W4405670013
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-09 ⓘ

This systematic review analyzed studies to determine the correlation between endometriosis and hypertensive disorders during pregnancy, finding that endometriosis may increase the risk of pregnancy-induced hypertension.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 · read from full text ⓘ

This systematic review investigated whether endometriosis is associated with hypertensive disorders during pregnancy by searching the Cochrane Library, PubMed, and Scopus up to the end of 2023. Included studies were full-text qualitative research in English that had definitive endometriosis diagnoses, with pregnant women without prior endometriosis as controls and women with endometriosis at any stage as the case group; two authors extracted data and a third resolved disagreements, with study quality assessed using the Downs and Black checklist. Using fixed- and random-effects models, the review found pregnancy-related hypertension disorders in 3,116 women with endometriosis, concluding that endometriosis may increase the risk of pregnancy-induced hypertension and related hypertensive conditions. The paper notes the evidence base is limited to the included qualitative full-text studies and their quality as evaluated by the checklist. This paper is centrally about endometriosis — it systematically reviews its connection to hypertensive disorders during pregnancy.

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Abstract

This study is designed to explore the correlation between endometriosis and hypertensive disorders during pregnancy. We looked through the Cochrane Library, PubMed and Scopus, for pertinent papers to the end of 2023. Included were full-text qualitative research studies that were published in English and provided a definitive diagnosis of endometriosis. While pregnant women without a prior endometriosis diagnosis made up the control group, pregnant women having an endometriosis diagnosis at any stage were included in the case group. The data was separately extracted and examined by two authors. A third author reviewed the entire manuscript to resolve disagreements. Data extraction and screening were done using Endnote X9. Review Manager 5.3's fixed and random effects models were employed to examine the combined data. The Downs and Black checklist were used to evaluate the included studies' quality. This analysis found that pregnancy-related hypertension disorder in 3116 endometriosis-affected women. The study confirmed that endometriosis may raise the risk of pregnancy-induced hypertension and conditions related to hypertension. Raising knowledge of hypertension diseases during pregnancy will help create screening and early diagnosis strategies that are effective.
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Determine the Connection Between Endometriosis and Hypertensive Disorders During Pregnancy: A Systematic Review DOI: https://doi.org/10.69667/amj.25101Keywords: Endometriosis, Hypertensive Disorders, Systematic ReviewAbstract This study is designed to explore the correlation between endometriosis and hypertensive disorders during pregnancy. We looked through the Cochrane Library, PubMed and Scopus, for pertinent papers to the end of 2023. Included were full-text qualitative research studies that were published in English and provided a definitive diagnosis of endometriosis. While pregnant women without a prior endometriosis diagnosis made up the control group, pregnant women having an endometriosis diagnosis at any stage were included in the case group. The data was separately extracted and examined by two authors. A third author reviewed the entire manuscript to resolve disagreements. Data extraction and screening were done using Endnote X9. Review Manager 5.3's fixed and random effects models were employed to examine the combined data. The Downs and Black checklist were used to evaluate the included studies' quality. This analysis found that pregnancy-related hypertension disorder in 3116 endometriosis-affected women. The study confirmed that endometriosis may raise the risk of pregnancy-induced hypertension and conditions related to hypertension. Raising knowledge of hypertension diseases during pregnancy will help create screening and early diagnosis strategies that are effective. تم تصميم هذه الدراسة لاستكشاف العلاقة بين بطانة الرحم واضطرابات ارتفاع ضغط الدم أثناء الحمل. لقد بحثنا في مكتبة كوكرين، ببميد، وسكوبس عن أوراق ذات صلة حتى نهاية عام 2023. وشملت دراسات بحثية نوعية كاملة النص نُشرت باللغة الإنجليزية وقدمت تشخيصًا نهائيًا لبطانة الرحم. بينما شكلت النساء الحوامل دون تشخيص سابق لبطانة الرحم مجموعة التحكم، تم تضمين النساء الحوامل المصابات ببطانة الرحم في أي مرحلة في مجموعة الحالة. تم استخراج البيانات وفحصها بشكل منفصل من قبل مؤلفين. قام مؤلف ثالث بمراجعة المخطوطة بأكملها لحل الخلافات. تم استخراج البيانات وفحصها باستخدام Endnote X9. تم استخدام نماذج التأثيرات الثابتة والعشوائية لـ Review Manager 5.3 لفحص البيانات المجمعة. تم استخدام قائمة التحقق Downs and Black لتقييم جودة الدراسات المشمولة. وجد هذا التحليل أن اضطراب ارتفاع ضغط الدم المرتبط بالحمل في 3116 امرأة مصابة ببطانة الرحم. وأكدت الدراسة أن مرض بطانة الرحم قد يزيد من خطر الإصابة بارتفاع ضغط الدم أثناء الحمل والحالات المرتبطة بارتفاع ضغط الدم. ومن شأن زيادة المعرفة بأمراض ارتفاع ضغط الدم أثناء الحمل أن يساعد في وضع استراتيجيات فعالة للفحص والتشخيص المبكر.

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Condition tags

endometriosis

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