Drastic elevation of serum CA125, CA72-4 and CA19-9 levels during menses in a patient with probable endometriosis

A Imai, Atsushi Imai, Imai A, Shinji Horibe, S Horibe, Horibe S, Atsushi Takagi, Takagi A, A Takagi, Hiroshi Takagi, Takagi H, H Takagi, Teruhiko Tamaya, Tamaya T, T Tamaya
European journal of obstetrics, gynecology, and reproductive biology · 1998 · vol. 78(1) , pp. 79–81 · doi:10.1016/s0301-2115(98)00003-7 · PMID:9605454 · W2000356400
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This case report details a patient with probable endometriosis experiencing drastic elevations of serum CA125, CA72-4, and CA19-9 levels specifically during her menstrual period.

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Abstract

Levels of CA125, CA72-4 and CA19-9, serum markers for ovarian cancer, were measured throughout menstrual cycles in a patient with probable pelvic endometriosis. The patient had CA125 levels >1000 U ml(-1), CA72-4>10 U ml(-1) and CA19-9>150 U ml(-1) during but not after menses (P<0.01). In luteal phase and premenstrual phase, the levels of these markers seemed to return normal ranges, although CA125 remained over the upper normal limit. Knowledge that a physiological elevation of these markers may occur during menses might avoid misinterpretation.

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Condition tags

endometriosis

MeSH descriptors

Antigens, Tumor-Associated, Carbohydrate CA-125 Antigen CA-19-9 Antigen Endometriosis Menstrual Cycle Menstrual Cycle Adnexal Diseases Adnexal Diseases Adnexal Diseases Adult Adult Antigens, Tumor-Associated, Carbohydrate Antigens, Tumor-Associated, Carbohydrate Buserelin Buserelin Buserelin CA-125 Antigen CA-125 Antigen CA-19-9 Antigen CA-19-9 Antigen

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (14)

Cited by (9)

Source provenance

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