Drastic elevation of serum CA125, CA72-4 and CA19-9 levels during menses in a patient with probable endometriosis

A Imai, Atsushi Imai, Imai A, Shinji Horibe, S Horibe, Horibe S, Atsushi Takagi, Takagi A, A Takagi, Hiroshi Takagi, Takagi H, H Takagi, Teruhiko Tamaya, Tamaya T, T Tamaya
European journal of obstetrics, gynecology, and reproductive biology · 1998 · vol. 78(1) , pp. 79–81 · doi:10.1016/s0301-2115(98)00003-7 · PMID:9605454 · W2000356400
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This case report details a patient with probable endometriosis experiencing drastic elevations of serum CA125, CA72-4, and CA19-9 levels specifically during her menstrual period.

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Abstract

Levels of CA125, CA72-4 and CA19-9, serum markers for ovarian cancer, were measured throughout menstrual cycles in a patient with probable pelvic endometriosis. The patient had CA125 levels >1000 U ml(-1), CA72-4>10 U ml(-1) and CA19-9>150 U ml(-1) during but not after menses (P<0.01). In luteal phase and premenstrual phase, the levels of these markers seemed to return normal ranges, although CA125 remained over the upper normal limit. Knowledge that a physiological elevation of these markers may occur during menses might avoid misinterpretation.

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Condition tags

endometriosis

MeSH descriptors

Antigens, Tumor-Associated, Carbohydrate CA-125 Antigen CA-19-9 Antigen Endometriosis Menstrual Cycle Adnexal Diseases Adnexal Diseases Adult Antigens, Tumor-Associated, Carbohydrate Buserelin Buserelin CA-125 Antigen CA-19-9 Antigen Cysts Cysts Endometriosis Endometriosis Endometriosis Female Humans

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (14)

Cited by (9)

Source provenance

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