COMPARATIVE ANALYSIS OF THE EFFECTIVENESS OF LAPAROSCOPIC ORGAN-PRESERVING TREATMENT OF DEEP ENDOMETRIOSIS USING THE STANDARDIZED METHOD AND THE TRADITIONAL METHOD

K.D. HAIDARZHI, G. L. Lavrynenko, И. З. Гладчук
In: The Odessa Medical Journal · 2025 · pp. 60–65 · doi:10.32782/2226-2008-2025-2-10 · W4411791026
article OA: gold CC0
🔓 Open OA copy Full text JSON View on OpenAlex View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

A standardized laparoscopic technique for deep endometriosis reduced operation time, blood loss, hospital stay, and certain complications compared to traditional methods, with similar pain reduction.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text ⓘ

This comparative study included 309 reproductive-age women with a pain syndrome who underwent laparoscopic organ-preserving surgery for deep endometriosis, comparing a standardized technique versus a traditional method, with outcomes assessed intraoperatively and early postoperatively and then pain at 6 months. The standardized approach showed shorter operative time (122.32 ± 2.61 vs 148.44 ± 3.05 minutes, p < 0.001), reduced blood loss (136.13 ± 2.41 vs 174.43 ± 3.23 mL, p < 0.001), shorter hospital stay (4.17 ± 0.1 vs 5.42 ± 0.16 days, p < 0.001), and fewer Clavien-Dindo grade I complications (notably ileus decreased 4.9-fold; fever 3.2-fold; urinary dysfunction 4.2-fold), while there was no difference in grade II–IV complications. Pain scores decreased at 6 months in both groups without a statistically significant between-group difference. The paper relates directly to endometriosis—specifically it evaluates laparoscopic organ-preserving treatment methods for deep endometriosis and their effect on surgical outcomes and pain.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

Deep endometriosis is the most aggressive type of endometriosis with deep tissue infiltration, leading to disruption of the anatomy and functionality of vital organs and a decrease in the quality of life.The aim of the study. To conduct a comparative analysis of intraoperative and postoperative indicators of organ-preserving surgical treatment of women with deep endometriosis accompanied by pain syndrome, using a standardized technique and a traditional laparoscopic method.Materials and methods. A comparative study was conducted, involving 309 patients of reproductive age with pain syndrome, who underwent surgery for deep endometriosis. The main group (I clinical) consisted of 210 patients who were operated on using the standardized method proposed by us. The comparison group (II clinical) consisted of 99 patients who were operated on using the traditional laparoscopic method.Results. Improvement of intraoperative parameters was obtained in the main group, in particular, a reduction in the duration of the operation (122.32 ± 2.61 min in the main group and 148.44 ± 3.05 min in the control group, p < 0.001), reduction in blood loss (136.13 ± 2.41 ml in the main group and 174.43 ± 3.23 ml in the control group, p < 0.001); early postoperative indicators, namely, a decrease in the duration of hospital stay (in the main group 4.17 ± 0.1 days and in the control group 5.42 ± 0.16 days, p < 0.001); reduction of Clavien-Dindo class I complications (cases of postoperative intestinal paresis decreased by 4.9 times, the number of cases of urination dysfunction – by 4.2 times). In both group, no difference was found in Clavien-Dindo class II, III and IV complications. A significant reduction in pain scores was obtained 6 month after surgery in both groups, with no significant difference between the groups.Conclusions. The use of a standardized surgical intervention algorithm helps improve some intraoperative and early postoperative indicators of surgical treatment of deep endometriosis.
Full text 5,219 characters · extracted from oa-doi-fallback · click to expand
ПОРІВНЯЛЬНИЙ АНАЛІЗ ЕФЕКТИВНОСТІ ЛАПАРОСКОПІЧНОГО ОРГАНОЗБЕРІГАЮЧОГО ЛІКУВАННЯ ГЛИБОКОГО ЕНДОМЕТРІОЗУ ЗА СТАНДАРТИЗОВАНОЮ МЕТОДИКОЮ ТА КЛАСИЧНИМ МЕТОДОМ DOI: https://doi.org/10.32782/2226-2008-2025-2-10Ключові слова: глибокий ендометріоз, хірургічне лікування, лапароскопічна хірургія, больовий синдром, #EnzianАнотація Проведено порівняльне дослідження, у яке включено 309 пацієнток репродуктивного віку з больовим синдромом, прооперованих з приводу глибокого ендометріозу. Отримано покращення інтраопераційних показників в основній групі, зокрема зменшення тривалості операції (122,32 ± 2,61 хв в основній групі та 148,44 ± 3,05 хв – у контрольній, р < 0,001), зменшення об’єму крововтрати (136,13 ± 2,41 мл в основній групі та 174,43 ± 3,23 мл – у контрольній, p < 0,001); ранніх післяопераційних показників, а саме зменшення тривалості перебування в стаціонарі (в основній групі 4,17 ± 0,1 дн. та в контрольній – 5,42 ± 0,16 дн., p < 0,001); зменшення ускладнень I класу за Clavien-Dindo (випадки післяопераційного парезу кишківника зменшились у 4,9 раза, кількість випадків лихоманки – у 3,2 раза, кількість випадків дисфункції сечовипускання – у 4,2 раза). В обох групах не отримано різниці в ускладненнях класу II, III, IV за Clavien-Dindo. Отримано суттєве зниження показників больового синдрому через 6 місяців після операції в обох групах, без достовірної різниці між групами. Посилання Zaporozhan V, Gladchuk I, Rozhkovska N, Haidarzhi KD. Deep endometriosis: overview of current recommendations and own data. Sci Dig Assoc Obstet Gynecol Ukr. 2022; 2(50): 26–36 https://doi.org/10.35278/2664-0767.2(50).2023.274979. Pedro do Valle Varela J, Berzoini Albuquerque AC, Pickert FS, et al. Surgical approach in the treatment of deep endometrio- sis. Health Soc. 2025; 5(1): 36–45. https://doi.org/10.51249/hs.v5i01.2384. Frumkin N, Schmädecker R, Isermann R, Keckstein J, Ulrich UA. Surgical Treatment of Deep Endometriosis. Geburtshilfe Und Frauenheilkd. 2023; 83(01): 79–87. https://doi.org/10.1055/a-1799-2658. Becker CM, Bokor A, Heikinheimo O, et al. ESHRE guideline: endometriosis. Hum Reprod Open. 2022; 2: hoac009. https://doi.org/10.1093/hropen/hoac009. Keckstein J, Becker CM, Canis M, et al. Recommendations for the surgical treatment of endometriosis. Part 2: deep endo- metriosis. Hum Reprod Open. 2020; 1: hoaa002. https://doi.org/10.1093/hropen/hoaa002. D’Alterio MN, Saponara S, D’Ancona G, et al. Role of surgical treatment in endometriosis. Minerva Obstet Gynecol. 2021; 73: 317–32. DOI: 10.23736/S2724-606X.21.04737-7. Burghaus S, Schäfer SD, Beckmann MW, et al. Diagnosis and Treatment of Endometriosis. Geburtshilfe Und Frauenheilkd. 2021; 81(04): 422–46. https://doi.org/10.1055/a-1380-3693. Haidarzhi KhD, Hladchuk IZ. Standartization of organ-preserving laparoscopic treatment of women with pain syndrome associated with deep endometriosis. Akt. pytannia pediatrii, akusherstva ta hinekolohii. 2025; 2: 38–47 (in Ukrainian). https://doi.org/10.11603/24116-4944.2024.2.15083. Keckstein J, Hoopmann M, Merz E, et al. Expert opinion on the use of transvaginal sonography for presurgical staging and classification of endometriosis. Arch Gynecol Obstet. 2023; 307: 5–19. https://doi.org/10.1007/s00404-022-06766-z. Guerriero S, Condous G, van den Bosch T, et al. Systematic approach to sonographic evaluation of the pelvis in women with suspected endometriosis, including terms, definitions and measurements: a consensus opinion from the International Deep Endometriosis Analysis (IDEA) group. Ultrasound Obstet Amp Gynecol. 2016; 48(3): 318–32. https://doi.org/10.1002/ uog.15955. Keckstein J, Saridogan E, Ulrich UA, et al. The #Enzian classification: A comprehensive non‐invasive and surgical descrip- tion system for endometriosis. Acta Obstet Gynecol Scand. 2021; 100: 1165–1175. https://doi.org/10.1111/aogs.14099. Bourdel N, Alves J, Pickering G, Ramilo I, Roman H, Canis M. Systematic review of endometriosis pain assessment: how to choose a scale? Hum Reprod Update. 2014; 21(1): 136–52. https://doi.org/10.1093/humupd/dmu046. Metzemaekers J, Bouwman L, de Vos M, et al. Clavien-Dindo, comprehensive complication index and classification of intraoperative adverse events: a uniform and holistic approach in adverse event registration for (deep) endometriosis surgery. Hum Reprod Open. 2023; 2: hoad019 https://doi.org/10.1093/hropen/hoad019. Leng L. Statistical Computing With R: (2nd ed.). Journal of the American Statistical Association. 2023; 115(531): 1557–1558. https://doi.org/10.1080/01621459.2020.1801280. Gladchuk I, Haidarzhi KD. Subtypes of deep endometriosis according to laparoscopic revision. Sci. Dig. Assoc. Obstet. Gynecol. Ukr. 2023; 1(51): 5–10. https://doi.org/10.35278/2664-0767.1(51).2023.294837. Larraín D, Buckel H, Prado J, Abedrapo M, Rojas I. Multidisciplinary laparoscopic management of deep infiltrating endometriosis from 2010 to 2017: A retrospective cohort study. Medwave. 2019; 19(11): e7750. https://doi.org/10.5867/medwave.2019.11.7750 Donnez O, Roman H. Choosing the right surgical technique for deep endometriosis: shaving, disc excision, or bowel resec- tion? Fertil Steril. 2017; 108(6): 93142. https://doi.org/10.1016/j.fertnstert.2017.09.006.

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Outcome instruments

Enzian

Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (17)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK